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HAMAP rule MF_00230

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General rule information [?]

Accession MF_00230
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 32)
Name CobT
Scope(s) Bacteria
Template(s) P36562 (COBT_ECOLI); Q05603 (COBT_SALTY); [ Recover all ]
Triggered by HAMAP; MF_00230 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier COBT
Protein name RecName: Full=Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase;
                 Short=NN:DBI PRT;
AltName: Full=N(1)-alpha-phosphoribosyltransferase;
Gene name Name=cobT;

Comments [?]

FUNCTIONCatalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
CATALYTIC ACTIVITY Reaction=5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate; Xref=Rhea:RHEA:11196, ChEBI:CHEBI:15378, ChEBI:CHEBI:15890, ChEBI:CHEBI:32544, ChEBI:CHEBI:57502, ChEBI:CHEBI:57918; EC=;
PATHWAYNucleoside biosynthesis; alpha-ribazole biosynthesis; alpha- ribazole from 5,6-dimethylbenzimidazole: step 1/2.
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
end case
SIMILARITYBelongs to the CobT family.

Keywords [?]

Gene Ontology [?]

GO:0008939; Molecular function:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity

Cross-references [?]

Pfam PF02277; DBI_PRT; 1;
NCBIfam TIGR03160; cobT_DBIPRT; 1;

Features [?]

From: COBT_ECOLI (P36562)
Key From To Description Tag Condition FTGroup
ACT_SITE 318 318 /note="Proton acceptor"

Additional information [?]

Size range 334-375 amino acids
Related rules None
Fusion Nter: None Cter: None

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