HAMAP rule MF_00230

General rule information [?]

Accession	MF_00230
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 32)

Name

CobT

Scope

Bacteria

Templates

P36562 (COBT_ECOLI); Q05603 (COBT_SALTY): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

COBT

Protein name

RecName:		Full=Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase;
		Short=NN:DBI PRT;
		EC 2.4.2.21;
AltName:		Full=N(1)-alpha-phosphoribosyltransferase;

Gene name

cobT

Comments [?]

Function	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
Catalytic activity	RHEA:11196: 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate EC 2.4.2.21
Pathway	Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2.

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>

Subunit

Homodimer.

end case

Similarity

Belongs to the CobT family.

Keywords [?]

Gene Ontology [?]

GO:0008939; Molecular function: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity.

Cross-references [?]

Pfam	PF02277; DBI_PRT; 1;
NCBIfam	TIGR03160; cobT_DBIPRT; 1;

Features [?]

From: COBT_ECOLI (P36562)

Key From To Description Tag Condition FTGroup

ACT_SITE 318 318 Proton acceptor

Additional information [?]