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Annotation rule MF_00230
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General rule information [?]

Accession MF_00230
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 31)
Name CobT
Scope
Bacteria
Templates P36562 (COBT_ECOLI); Q05603 (COBT_SALTY): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
COBT
Protein name
RecName: Full=Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase;
Short=NN:DBI PRT;
EC 2.4.2.21;
AltName: Full=N(1)-alpha-phosphoribosyltransferase;
Gene name
cobT

Comments [?]

Function Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
Catalytic activity RHEA:11196: 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate
EC 2.4.2.21
Pathway Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2.
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Subunit Homodimer.
end case
Similarity Belongs to the CobT family.

Keywords [?]


Gene Ontology [?]

GO:0008939; Molecular function: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity.

Cross-references [?]

Pfam PF02277; DBI_PRT; 1;
TIGRFAMs TIGR03160; cobT_DBIPRT; 1;

Features [?]

From: COBT_ECOLI (P36562)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     318     318       Proton acceptor        

Additional information [?]

Size range 334-375 amino acids
Related rules None
Fusion None