HAMAP rule MF_00231

General rule information [?]

Accession	MF_00231
Dates	1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 20)

Name	eIF_2_alpha

Scope

Archaea

Template

P20459 (IF2A_YEAST)

Triggered by

HAMAP; MF_00231 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

IF2A

Protein name

RecName:		Full=Translation initiation factor 2 subunit alpha;
AltName:		Full=aIF2-alpha;
AltName:		Full=eIF-2-alpha;

Gene name

eif2a

Comments [?]

Function	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
Subunit	Heterotrimer composed of an alpha, a beta and a gamma chain.
Similarity	Belongs to the eIF-2-alpha family.

Keywords [?]

Initiation factor
Protein biosynthesis
RNA-binding

Gene Ontology [?]

GO:0003723; Molecular function: RNA binding.
GO:0003743; Molecular function: translation initiation factor activity.
GO:0006413; Biological process: translational initiation.

Cross-references [?]

Pfam	PF00575; S1; 1;
PROSITE	PS50126; S1; 1; trigger=PRU00180;

Additional information [?]

Size range	254-277 amino acids
Related rules	None
Fusion	None

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