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HAMAP rule MF_00237

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General rule information [?]

Accession MF_00237
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 41)
Name TatB
Scope(s) Bacteria
Template(s) P69425 (TATB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00237 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TATB
case <OC:Pseudomonadota> or <OC:Actinomycetota>
RecName: Full=Sec-independent protein translocase protein TatB;
Gene name Name=tatB;
RecName: Full=Sec-independent protein translocase protein TatB homolog;
end case

Comments [?]

case <OC:Pseudomonadota> or <OC:Actinomycetota>
FUNCTIONPart of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
SUBUNITThe Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Single-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Single-pass membrane protein.
end case
SIMILARITYBelongs to the TatB family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Protein transport
Transmembrane helix

Gene Ontology [?]

GO:0008320; Molecular function:protein transmembrane transporter activity
GO:0043953; Biological process:protein transport by the Tat complex
GO:0005886; Cellular component:plasma membrane
GO:0033281; Cellular component:TAT protein transport complex

Cross-references [?]

Pfam PF02416; MttA_Hcf106; 1;
NCBIfam TIGR01410; TatB; 1;

Features [?]

From: TATB_ECOLI (P69425)
Key From To Description Tag Condition FTGroup
TRANSMEM 1 21 /note="Helical"

Additional information [?]

Size range 110-246 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments The Tat system is composed of TatA, TatB and TatC subunits in Gram-negative bacteria and in Actinomycetota, and of TatA and TatC subunits in most Gram-positive bacteria.

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