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HAMAP rule MF_00237

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General rule information [?]

Accession MF_00237
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 41)
Name TatB
Template P69425 (TATB_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

case <OC:Pseudomonadota> or <OC:Actinomycetota>
Protein name
RecName: Full=Sec-independent protein translocase protein TatB;
Gene name
Protein name
RecName: Full=Sec-independent protein translocase protein TatB homolog;
end case

Comments [?]

case <OC:Pseudomonadota> or <OC:Actinomycetota>
Function Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
Subunit The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Single-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Single-pass membrane protein.
end case
Similarity Belongs to the TatB family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0008320; Molecular function: protein transmembrane transporter activity.
GO:0043953; Biological process: protein transport by the Tat complex.
GO:0005886; Cellular component: plasma membrane.
GO:0033281; Cellular component: TAT protein transport complex.

Cross-references [?]

Pfam PF02416; MttA_Hcf106; 1;
NCBIfam TIGR01410; TatB; 1;

Features [?]

From: TATB_ECOLI (P69425)
Key     From     To       Description   Tag   Condition   FTGroup
TRANSMEM     1     21       Helical        

Additional information [?]

Size range 110-246 amino acids
Related rules None
Fusion None
Comments The Tat system is composed of TatA, TatB and TatC subunits in Gram-negative bacteria and in Actinomycetota, and of TatA and TatC subunits in most Gram-positive bacteria.