HAMAP rule MF_00237
General rule information
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Accession | MF_00237 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 41) |
Name | TatB |
Scope | Bacteria |
Template | P69425 (TATB_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
|
case <OC:Pseudomonadota> or <OC:Actinomycetota>
Protein name |
|
Gene name |
|
else
Protein name |
|
end case
Comments
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case <OC:Pseudomonadota> or <OC:Actinomycetota>
Function | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. |
Subunit | The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. |
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location | Cell membrane; Single-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location | Cell inner membrane; Single-pass membrane protein. |
end case
Similarity | Belongs to the TatB family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0008320; Molecular function: protein transmembrane transporter activity.
GO:0043953; Biological process: protein transport by the Tat complex.
GO:0005886; Cellular component: plasma membrane.
GO:0033281; Cellular component: TAT protein transport complex.
GO:0043953; Biological process: protein transport by the Tat complex.
GO:0005886; Cellular component: plasma membrane.
GO:0033281; Cellular component: TAT protein transport complex.
Cross-references
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Features
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From: TATB_ECOLI (P69425) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TRANSMEM | 1 | 21 | Helical |
Additional information
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Size range | 110-246 amino acids |
Related rules | None |
Fusion | None |
Comments | The Tat system is composed of TatA, TatB and TatC subunits in Gram-negative bacteria and in Actinomycetota, and of TatA and TatC subunits in most Gram-positive bacteria. |