HAMAP rule MF_00237
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00237 |
| Accession | MF_00237 |
| Dates | 28-FEB-2005 (Created)
01-JUN-2023 (Last updated, Version 31) |
| Name | TatB |
| Scope(s) |
Bacteria |
| Template(s) | P69425; [ Recover all ] |
| Triggered by |
HAMAP; MF_00237 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TATB |
| case <OC:Pseudomonadota> or <OC:Actinomycetota> | |
| Protein name | RecName: Full=Sec-independent protein translocase protein TatB; |
| Gene name | Name=tatB; |
| else | |
| Protein name | RecName: Full=Sec-independent protein translocase protein TatB homolog; |
| end case | |
Comments
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| case <OC:Pseudomonadota> or <OC:Actinomycetota> | |
| FUNCTION | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. |
| SUBUNIT | The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. |
| end case | |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the TatB family. |
Keywords
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| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Membrane | |
| Protein transport | |
| Transport | |
| Translocation | |
| Transmembrane | |
| Transmembrane helix | |
Gene Ontology
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| GO:0008320; Molecular function:protein transmembrane transporter activity |
| GO:0043953; Biological process:protein transport by the Tat complex |
| GO:0005886; Cellular component:plasma membrane |
| GO:0033281; Cellular component:TAT protein transport complex |
Cross-references
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Features
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| From: TATB_ECOLI (P69425) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TRANSMEM | 1 | 21 | /note="Helical" | |||||||||
Additional information
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| Size range | 110-246 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | The Tat system is composed of TatA, TatB and TatC subunits in Gram-negative bacteria and in Actinomycetota, and of TatA and TatC subunits in most Gram-positive bacteria. |