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HAMAP rule MF_00238

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General rule information [?]

Accession MF_00238
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 35)
Name Cytidyl_kinase_type1
Bacteria; except Cyanobacteriota
Templates P0A6I0 (KCY_ECOLI); P38493 (KCY_BACSU); P9WPA9 (KCY_MYCTU): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Cytidylate kinase;
AltName: Full=Cytidine monophosphate kinase;
Short=CMP kinase;
Gene name

Comments [?]

Catalytic activity RHEA:11600: ATP + CMP = ADP + CDP
RHEA:25094: ATP + dCMP = ADP + dCDP
Subcellular location Cytoplasm.
Similarity Belongs to the cytidylate kinase family. Type 1 subfamily.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004127; Molecular function: cytidylate kinase activity.
GO:0006220; Biological process: pyrimidine nucleotide metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02224; Cytidylate_kin; 1;
NCBIfam TIGR00017; Cmk; 1;

Features [?]

From: KCY_ECOLI (P0A6I0)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     12     20       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-x(2)-[GSA]-x-G-K-[GST]-[STAV]  

Additional information [?]

Size range 206-235 amino acids
Related rules MF_00239 (KCY); MF_01349 (PANCY supersedes the current rule)
Fusion None
Comments In Cyanobacteriota this protein is fused N-terminally to pantoate-- beta-alanine ligase (see MF_01349). BORBU and BORGP also have a subfamily 2 enzyme.