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HAMAP rule MF_00238

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General rule information [?]

Accession MF_00238
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 35)
Name Cytidyl_kinase_type1
Scope(s) Bacteria
Template(s) P0A6I0 (KCY_ECOLI); P38493 (KCY_BACSU); P9WPA9 (KCY_MYCTU); [ Recover all ]
Triggered by HAMAP; MF_00238 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier KCY
Protein name RecName: Full=Cytidylate kinase;
AltName: Full=Cytidine monophosphate kinase;
                 Short=CMP kinase;
Gene name Name=cmk;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + CMP = ADP + CDP; Xref=Rhea:RHEA:11600, ChEBI:CHEBI:30616, ChEBI:CHEBI:58069, ChEBI:CHEBI:60377, ChEBI:CHEBI:456216; EC=;
CATALYTIC ACTIVITY Reaction=ATP + dCMP = ADP + dCDP; Xref=Rhea:RHEA:25094, ChEBI:CHEBI:30616, ChEBI:CHEBI:57566, ChEBI:CHEBI:58593, ChEBI:CHEBI:456216; EC=;
SIMILARITYBelongs to the cytidylate kinase family. Type 1 subfamily.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0004127; Molecular function:cytidylate kinase activity
GO:0006220; Biological process:pyrimidine nucleotide metabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02224; Cytidylate_kin; 1;
NCBIfam TIGR00017; Cmk; 1;

Features [?]

From: KCY_ECOLI (P0A6I0)
Key From To Description Tag Condition FTGroup
BINDING 12 20 /ligand="ATP"

Additional information [?]

Size range 206-235 amino acids
Related rules MF_00239
Fusion Nter: None Cter: None
Comments In Cyanobacteriota this protein is fused N-terminally to pantoate-- beta-alanine ligase (see MF_01349). BORBU and BORGP also have a subfamily 2 enzyme.

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