HAMAP logo

HAMAP rule MF_00239

Send feedback

General rule information [?]

Accession MF_00239
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 31)
Name Cytidyl_kinase_type2
Scope
Bacteria
Archaea
Templates P0A6I0 (KCY_ECOLI); P38493 (KCY_BACSU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
KCY
Protein name
RecName: Full=Cytidylate kinase;
Short=CK;
EC 2.7.4.25;
AltName: Full=Cytidine monophosphate kinase;
Short=CMP kinase;
Gene name
cmk

Comments [?]

Catalytic activity RHEA:11600: ATP + CMP = ADP + CDP
EC 2.7.4.25
RHEA:25094: ATP + dCMP = ADP + dCDP
EC 2.7.4.25
Subcellular location Cytoplasm.
Similarity Belongs to the cytidylate kinase family. Type 2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004127; Molecular function: cytidylate kinase activity.
GO:0006220; Biological process: pyrimidine nucleotide metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02224; Cytidylate_kin; 1;
TIGRFAMs TIGR02173; Cyt_kin_arch; 1;

Features [?]

From: KCY_METJA (Q58071)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     7     15       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-x(2)-G-x-G-x-[ST]-[ST]  

Additional information [?]

Size range 161-193 amino acids
Related rules MF_00238 (KCY)
Fusion None
Comments Generally found in archaea, but also present in a few bacterial species BORBU and BORGP also have a subfamily 1 enzyme