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Annotation rule MF_00240 |
Accession | MF_00240 |
Dates | 1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 19) |
Name | LolA |
Scope | Bacteria; Proteobacteria |
Template | P61316 (LOLA_ECOLI) |
Triggered by |
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Protein name |
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Gene name |
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Function | Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). |
Subunit | Monomer. |
Subcellular location | Periplasm. |
Similarity | Belongs to the LolA family. |
General | Signal; -; 1; trigger=yes; |
Size range | 169-215 amino acids |
Related rules | None |
Fusion | None |
Comments | The epsilon proteobacteria possess lolA but apparently they do not have lolB. Further characterization is needed to assess to which protein the outer membrane lipoproteins are translocated (the same applies to the animal symbionts Candidatus Blochmannia floridanus and Wigglesworthia glossinidia brevipalpis). |