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Annotation rule MF_00240
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General rule information [?]

Accession MF_00240
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 19)
Name LolA
Bacteria; Proteobacteria
Template P61316 (LOLA_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Outer-membrane lipoprotein carrier protein;
Flags: Precursor;
Gene name

Comments [?]

Function Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
Subunit Monomer.
Subcellular location Periplasm.
Similarity Belongs to the LolA family.

Keywords [?]

Gene Ontology [?]

GO:0044874; Biological process: lipoprotein localization to outer membrane.
GO:0042597; Cellular component: periplasmic space.

Cross-references [?]

Pfam PF03548; LolA; 1;
TIGRFAMs TIGR00547; LolA; 1;

Computed features [?]

General Signal; -; 1; trigger=yes;

Additional information [?]

Size range 169-215 amino acids
Related rules None
Fusion None
Comments The epsilon proteobacteria possess lolA but apparently they do not have lolB. Further characterization is needed to assess to which protein the outer membrane lipoproteins are translocated (the same applies to the animal symbionts Candidatus Blochmannia floridanus and Wigglesworthia glossinidia brevipalpis).