HAMAP rule MF_00242
General rule information
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| Accession | MF_00242 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 31) |
| Name | Arg_deiminase |
| Scope(s) |
Bacteria |
| Template(s) | O53088 (ARCA_LATSK); [ Recover all ] |
| Triggered by |
HAMAP; MF_00242 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ARCA |
| Protein name | RecName: Full=Arginine deiminase; Short=ADI; EC=3.5.3.6; AltName: Full=Arginine dihydrolase; Short=AD; |
| Gene name | Name=arcA; |
Comments
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| CATALYTIC ACTIVITY | Reaction=H2O + L-arginine = L-citrulline + NH4(+); Xref=Rhea:RHEA:19597, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:32682, ChEBI:CHEBI:57743; EC=3.5.3.6; |
| PATHWAY | Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 1/2. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the arginine deiminase family. |
Keywords
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Gene Ontology
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| GO:0016990; Molecular function:arginine deiminase activity |
| GO:0006527; Biological process:arginine catabolic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF02274; Amidinotransf; 1; |
| PIRSF | PIRSF006356; Arg_deiminase; 1; |
| PRINTS | PR01466; ARGDEIMINASE; 1; |
| NCBIfam | TIGR01078; ArcA; 1; |
Features
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| From: ARCA_LATSK (O53088) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 399 | 399 | /note="Amidino-cysteine intermediate" | C | ||||||||
Additional information
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| Size range | 402-420 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | There is a divergent second copy of arcA in MYCPN. The first copy shown here is a reconstruction and could be artefactual |