Home  |  Contact
Annotation rule MF_00243
Send feedback

General rule information [?]

Accession MF_00243
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 30)
Name NMN_adenylyltr
Scope
Bacteria
Archaea
Templates Q57961 (NADM_METJA); O26253 (NADM_METTH): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
NADM
Protein name
RecName: Full=Nicotinamide-nucleotide adenylyltransferase;
EC 2.7.7.1;
AltName: Full=NAD(+) diphosphorylase;
AltName: Full=NAD(+) pyrophosphorylase;
AltName: Full=NMN adenylyltransferase;

Comments [?]

Catalytic activity RHEA:21360: ATP + beta-nicotinamide D-ribonucleotide + H(+) = diphosphate + NAD(+)
EC 2.7.7.1
Pathway Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.
Subcellular location Cytoplasm.
Similarity Belongs to the archaeal NMN adenylyltransferase family.

Keywords [?]

ATP-binding
Cytoplasm
NAD
Nucleotide-binding
Nucleotidyltransferase
Pyridine nucleotide biosynthesis
Transferase

Gene Ontology [?]

GO:0000309; Molecular function: nicotinamide-nucleotide adenylyltransferase activity.
GO:0009435; Biological process: NAD biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01467; CTP_transf_2; 1;
TIGRFAMs TIGR01527; Arch_NMN_Atrans; 1;
TIGR00125; Cyt_tran_rel; 1;

Additional information [?]

Size range 168-188 amino acids
Related rules None
Fusion Nter: None; Cter: <Nudix>
Comments There are closely related homolog of nadD in ARCFU (AF1488) and AERPE (APE1986). Nudix-like C-terminal domain in SYNY3.


View rule in raw text format (no links)