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HAMAP rule MF_00243

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General rule information [?]

Accession MF_00243
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 31)
Name NMN_adenylyltr
Scope(s) Bacteria
Template(s) Q57961 (NADM_METJA); O26253 (NADM_METTH); [ Recover all ]
Triggered by HAMAP; MF_00243 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NADM
Protein name RecName: Full=Nicotinamide-nucleotide adenylyltransferase;
AltName: Full=NAD(+) diphosphorylase;
AltName: Full=NAD(+) pyrophosphorylase;
AltName: Full=NMN adenylyltransferase;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + beta-nicotinamide D-ribonucleotide + H(+) = diphosphate + NAD(+); Xref=Rhea:RHEA:21360, ChEBI:CHEBI:14649, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57540; EC=;
PATHWAYCofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.
SIMILARITYBelongs to the archaeal NMN adenylyltransferase family.

Keywords [?]

Gene Ontology [?]

GO:0000309; Molecular function:nicotinamide-nucleotide adenylyltransferase activity
GO:0009435; Biological process:NAD biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01467; CTP_transf_2; 1;
NCBIfam TIGR01527; Arch_NMN_Atrans; 1;
NCBIfam TIGR00125; Cyt_tran_rel; 1;

Features [?]

Additional information [?]

Size range 168-188 amino acids
Related rules None
Fusion Nter: None Cter: <Nudix>
Comments There are closely related homolog of nadD in ARCFU (AF1488) and AERPE (APE1986). Nudix-like C-terminal domain in SYNY3.

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