HAMAP rule MF_00244
General rule information
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Accession | MF_00244 |
Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 27) |
Name | NaMN_adenylyltr |
Scope(s) |
Bacteria |
Template(s) | P54455 (NADD_BACSU); P0A752 (NADD_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_00244 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | NADD |
Protein name | RecName: Full=Probable nicotinate-nucleotide adenylyltransferase; EC=2.7.7.18; AltName: Full=Deamido-NAD(+) diphosphorylase; AltName: Full=Deamido-NAD(+) pyrophosphorylase; AltName: Full=Nicotinate mononucleotide adenylyltransferase; Short=NaMN adenylyltransferase; |
Gene name | Name=nadD; |
Comments
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FUNCTION | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). |
CATALYTIC ACTIVITY | Reaction=ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate; Xref=Rhea:RHEA:22860, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57502, ChEBI:CHEBI:58437; EC=2.7.7.18; |
PATHWAY | Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1. |
SIMILARITY | Belongs to the NadD family. |
Keywords
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ATP-binding |
NAD |
Nucleotide-binding |
Nucleotidyltransferase |
Pyridine nucleotide biosynthesis |
Transferase |
Gene Ontology
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GO:0004515; Molecular function:nicotinate-nucleotide adenylyltransferase activity |
GO:0009435; Biological process:NAD biosynthetic process |
Cross-references
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Features
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Additional information
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Size range | 168-222 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: <Unknown> |
Comments | Distant relative in MYCGE (MG240) and MYCPN (MPN336). |