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HAMAP rule MF_00244

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General rule information [?]

Accession MF_00244
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 27)
Name NaMN_adenylyltr
Scope(s) Bacteria
Template(s) P54455 (NADD_BACSU); P0A752 (NADD_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00244 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NADD
Protein name RecName: Full=Probable nicotinate-nucleotide adenylyltransferase;
AltName: Full=Deamido-NAD(+) diphosphorylase;
AltName: Full=Deamido-NAD(+) pyrophosphorylase;
AltName: Full=Nicotinate mononucleotide adenylyltransferase;
                 Short=NaMN adenylyltransferase;
Gene name Name=nadD;

Comments [?]

FUNCTIONCatalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
CATALYTIC ACTIVITY Reaction=ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate; Xref=Rhea:RHEA:22860, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57502, ChEBI:CHEBI:58437; EC=;
PATHWAYCofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.
SIMILARITYBelongs to the NadD family.

Keywords [?]

Gene Ontology [?]

GO:0004515; Molecular function:nicotinate-nucleotide adenylyltransferase activity
GO:0009435; Biological process:NAD biosynthetic process

Cross-references [?]

Pfam PF01467; CTP_transf_2; 1;
NCBIfam TIGR00125; Cyt_tran_rel; 1;
NCBIfam TIGR00482; TIGR00482; 1;

Features [?]

Additional information [?]

Size range 168-222 amino acids
Related rules None
Fusion Nter: None Cter: <Unknown>
Comments Distant relative in MYCGE (MG240) and MYCPN (MPN336).

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