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Annotation rule MF_00244
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General rule information [?]

Accession MF_00244
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 26)
Name NaMN_adenylyltr
Scope
Bacteria
Templates P54455 (NADD_BACSU); P0A752 (NADD_ECOLI): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
NADD
Protein name
RecName: Full=Probable nicotinate-nucleotide adenylyltransferase;
EC 2.7.7.18;
AltName: Full=Deamido-NAD(+) diphosphorylase;
AltName: Full=Deamido-NAD(+) pyrophosphorylase;
AltName: Full=Nicotinate mononucleotide adenylyltransferase;
Short=NaMN adenylyltransferase;
Gene name
nadD

Comments [?]

Function Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
Catalytic activity RHEA:22860: ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate
EC 2.7.7.18
Pathway Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.
Similarity Belongs to the NadD family.

Keywords [?]

ATP-binding
NAD
Nucleotide-binding
Nucleotidyltransferase
Pyridine nucleotide biosynthesis
Transferase

Gene Ontology [?]

GO:0004515; Molecular function: nicotinate-nucleotide adenylyltransferase activity.
GO:0009435; Biological process: NAD biosynthetic process.

Cross-references [?]

Pfam PF01467; CTP_transf_2; 1;
TIGRFAMs TIGR00125; Cyt_tran_rel; 1;
TIGR00482; TIGR00482; 1;

Additional information [?]

Size range 168-222 amino acids
Related rules None
Fusion Nter: None; Cter: <Unknown>
Comments Distant relative in MYCGE (MG240) and MYCPN (MPN336).


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