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HAMAP rule MF_00250

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General rule information [?]

Accession MF_00250
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 27)
Name RNApol_arch_Rpo10
Scope(s) Archaea
Template(s) O26147 (RPO10_METTH); P39472 (RPO10_SULAC); B8YB63 (RPO10_SACSH); Q980Z8 (RPO10_SACS2); [ Recover all ]
Triggered by HAMAP; MF_00250 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RPO10
Protein name RecName: Full=DNA-directed RNA polymerase subunit Rpo10;
AltName: Full=DNA-directed RNA polymerase subunit N;
Gene name Name=rpo10; Synonyms=rpoN;

Comments [?]

FUNCTIONDNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
CATALYTIC ACTIVITY Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=;
case <FTGroup:1>
COFACTOR Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion.;
end case
SUBUNITPart of the RNA polymerase complex.
SIMILARITYBelongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm
GO:0003899; Molecular function:DNA-directed 5'-3' RNA polymerase activity
GO:0006351; Biological process:DNA-templated transcription
case <FTGroup:1>
GO:0008270; Molecular function:zinc ion binding
end case

Cross-references [?]

Pfam PF01194; RNA_pol_N; 1;

Features [?]

From: RPO10_METTH (O26147)
Key From To Description Tag Condition FTGroup
BINDING 6 6 /ligand="Zn(2+)"
C 1
BINDING 9 9 /ligand="Zn(2+)"
C 1
BINDING 43 43 /ligand="Zn(2+)"
C 1
BINDING 44 44 /ligand="Zn(2+)"
C 1

Additional information [?]

Size range 55-90 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Archaeoglobus species have a slightly longer N-terminus.

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