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HAMAP rule MF_00250
General rule information
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| Accession | MF_00250 |
| Dates | 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 27) |
| Name | RNApol_arch_Rpo10 |
| Scope(s) |
Archaea |
| Template(s) | O26147 (RPO10_METTH); P39472 (RPO10_SULAC); B8YB63 (RPO10_SACSH); Q980Z8 (RPO10_SACS2); [ Recover all ] |
| Triggered by |
HAMAP; MF_00250 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RPO10 |
| Protein name | RecName: Full=DNA-directed RNA polymerase subunit Rpo10; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase subunit N; |
| Gene name | Name=rpo10; Synonyms=rpoN; |
Comments
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| FUNCTION | DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. |
| CATALYTIC ACTIVITY | Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.6; |
| case <FTGroup:1> | |
| COFACTOR | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion.; |
| end case | |
| SUBUNIT | Part of the RNA polymerase complex. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family. |
Keywords
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| Cytoplasm | |
| Transferase | |
| Nucleotidyltransferase | |
| DNA-directed RNA polymerase | |
| Transcription | |
| case <FTGroup:1> | |
| Zinc | |
| Metal-binding | |
| end case | |
Gene Ontology
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| GO:0005737; Cellular component:cytoplasm | |
| GO:0003899; Molecular function:DNA-directed 5'-3' RNA polymerase activity | |
| GO:0006351; Biological process:DNA-templated transcription | |
| case <FTGroup:1> | |
| GO:0008270; Molecular function:zinc ion binding | |
| end case | |
Cross-references
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Features
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| From: RPO10_METTH (O26147) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 6 | 6 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 9 | 9 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 43 | 43 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
| BINDING | 44 | 44 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
C | 1 | |||||||
Additional information
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| Size range | 55-90 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Archaeoglobus species have a slightly longer N-terminus. |