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HAMAP rule MF_00250

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General rule information [?]

Accession MF_00250
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 27)
Name RNApol_arch_Rpo10
Scope
Archaea
Templates O26147 (RPO10_METTH); P39472 (RPO10_SULAC); B8YB63 (RPO10_SACSH); Q980Z8 (RPO10_SACS2): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RPO10
Protein name
RecName: Full=DNA-directed RNA polymerase subunit Rpo10;
EC 2.7.7.6;
AltName: Full=DNA-directed RNA polymerase subunit N;
Gene name
rpo10, rpoN

Comments [?]

Function DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity RHEA:21248: a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
EC 2.7.7.6
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion.
end case
Subunit Part of the RNA polymerase complex.
Subcellular location Cytoplasm.
Similarity Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

Keywords [?]

Cytoplasm
Transferase
Nucleotidyltransferase
DNA-directed RNA polymerase
Transcription
case <FTGroup:1>
Zinc
Metal-binding
end case

Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0003899; Molecular function: DNA-directed 5'-3' RNA polymerase activity.
GO:0006351; Biological process: DNA-templated transcription.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case

Cross-references [?]

Pfam PF01194; RNA_pol_N; 1;
PROSITE PS01112; RNA_POL_N_8KD; 1;

Features [?]

From: RPO10_METTH (O26147)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     6     6       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING     9     9       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING     43     43       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING     44     44       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1

Additional information [?]

Size range 55-90 amino acids
Related rules None
Fusion None
Comments Archaeoglobus species have a slightly longer N-terminus.


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