HAMAP rule MF_00258
General rule information
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| Accession | MF_00258 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 29) |
| Name | Glu_racemase |
| Scope(s) |
Bacteria |
| Template(s) | P22634 (MURI_ECOLI); P56868 (MURI_AQUPY); P94556 (MURI1_BACSU); Q836J0 (MURI_ENTFA); Q9ZLT0 (MURI_HELPJ); Q03469 (MURI_LIMFE); Q9A1B7 (MURI_STRP1); [ Recover all ] |
| Triggered by |
HAMAP; MF_00258 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MURI |
| Protein name | RecName: Full=Glutamate racemase; EC=5.1.1.3; |
| Gene name | Name=murI; |
Comments
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| FUNCTION | Provides the (R)-glutamate required for cell wall biosynthesis. |
| CATALYTIC ACTIVITY | Reaction=L-glutamate = D-glutamate; Xref=Rhea:RHEA:12813, ChEBI:CHEBI:29985, ChEBI:CHEBI:29986; EC=5.1.1.3; |
| PATHWAY | Cell wall biogenesis; peptidoglycan biosynthesis. |
| SIMILARITY | Belongs to the aspartate/glutamate racemases family. |
Keywords
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Gene Ontology
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| GO:0008881; Molecular function:glutamate racemase activity |
| GO:0009252; Biological process:peptidoglycan biosynthetic process |
Cross-references
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| Pfam | PF01177; Asp_Glu_race; 1; |
| NCBIfam | TIGR00067; glut_race; 1; |
| PROSITE | PS00923; ASP_GLU_RACEMASE_1; 1; |
| PROSITE | PS00924; ASP_GLU_RACEMASE_2; 1; |
Features
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| From: MURI_ECOLI (P22634) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 28 | 29 | /ligand="substrate" | D-S | ||||||||
| BINDING | 60 | 61 | /ligand="substrate" | [YF]-[GS] | ||||||||
| BINDING | 93 | 94 | /ligand="substrate" | N-[TS] | ||||||||
| BINDING | 205 | 206 | /ligand="substrate" | T-H | ||||||||
| ACT_SITE | 92 | 92 | /note="Proton donor/acceptor" | C | ||||||||
| ACT_SITE | 204 | 204 | /note="Proton donor/acceptor" | C | ||||||||
Additional information
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| Size range | 230-330 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |