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Annotation rule MF_00259
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General rule information [?]

Accession MF_00259
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 24)
Name GcvT
Scope
Bacteria
Archaea
Template P27248 (GCST_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GCST
case <OC:Bacteria>
Protein name
RecName: Full=Aminomethyltransferase;
EC 2.1.2.10;
AltName: Full=Glycine cleavage system T protein;
end case
case <OC:Archaea>
Protein name
RecName: Full=Probable aminomethyltransferase;
EC 2.1.2.10;
AltName: Full=Glycine cleavage system T protein;
end case
Gene name
gcvT

Comments [?]

Function The glycine cleavage system catalyzes the degradation of glycine.
Catalytic activity RHEA:16945: (6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)
EC 2.1.2.10
Subunit The glycine cleavage system is composed of four proteins: P, T, L and H.
Similarity Belongs to the GcvT family.

Keywords [?]


Gene Ontology [?]

GO:0004047; Molecular function: aminomethyltransferase activity.
GO:0019464; Biological process: glycine decarboxylation via glycine cleavage system.

Cross-references [?]

Pfam PF01571; GCV_T; 1;
TIGRFAMs TIGR00528; GcvT; 1;

Additional information [?]

Size range 349-401 amino acids
Related rules None
Fusion None