HAMAP rule MF_00259
General rule information
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Accession | MF_00259 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 25) |
Name | GcvT |
Scope | Bacteria
Archaea |
Template | P27248 (GCST_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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case <OC:Bacteria>
Protein name |
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end case
case <OC:Archaea>
Protein name |
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end case
Gene name |
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Comments
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Function | The glycine cleavage system catalyzes the degradation of glycine. |
Catalytic activity | RHEA:16945: (6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)
EC 2.1.2.10 |
Subunit | The glycine cleavage system is composed of four proteins: P, T, L and H. |
Similarity | Belongs to the GcvT family. |
Keywords
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Gene Ontology
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GO:0004047; Molecular function: aminomethyltransferase activity.
GO:0019464; Biological process: glycine decarboxylation via glycine cleavage system.
GO:0019464; Biological process: glycine decarboxylation via glycine cleavage system.
Cross-references
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Additional information
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Size range | 349-401 amino acids |
Related rules | None |
Fusion | None |