HAMAP rule MF_00259

General rule information [?]

Accession	MF_00259
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 25)

Name

GcvT

Scope

Bacteria

Archaea

Template

P27248 (GCST_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

GCST

case <OC:Bacteria>

Protein name

RecName:		Full=Aminomethyltransferase;
		EC 2.1.2.10;
AltName:		Full=Glycine cleavage system T protein;

end case

case <OC:Archaea>

Protein name

RecName:		Full=Probable aminomethyltransferase;
		EC 2.1.2.10;
AltName:		Full=Glycine cleavage system T protein;

end case

Gene name

gcvT

Comments [?]

Function	The glycine cleavage system catalyzes the degradation of glycine.
Catalytic activity	RHEA:16945: (6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+) EC 2.1.2.10
Subunit	The glycine cleavage system is composed of four proteins: P, T, L and H.
Similarity	Belongs to the GcvT family.

Keywords [?]

Gene Ontology [?]

GO:0004047; Molecular function: aminomethyltransferase activity.
GO:0019464; Biological process: glycine decarboxylation via glycine cleavage system.

Cross-references [?]

Pfam	PF01571; GCV_T; 1;
NCBIfam	TIGR00528; GcvT; 1;

Additional information [?]