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HAMAP rule MF_00266

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General rule information [?]

Accession MF_00266
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 22)
Name TYW3_archaea
Scope(s) Archaea
Template(s) P53177 (TYW3_YEAST); [ Recover all ]
Triggered by HAMAP; MF_00266 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TYW3
Protein name RecName: Full=tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase;
AltName: Full=tRNA wyosine derivatives biosynthesis protein Taw3;
Gene name Name=taw3;

Comments [?]

FUNCTIONS-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
CATALYTIC ACTIVITY Reaction=4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3- carboxypropyl]wyosine(37) in tRNA(Phe) + H(+) + S-adenosyl-L- homocysteine; Xref=Rhea:RHEA:36635, Rhea:RHEA-COMP:10378, Rhea:RHEA- COMP:10379, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:73543, ChEBI:CHEBI:73550; EC=;
SIMILARITYBelongs to the TYW3 family.

Keywords [?]

Gene Ontology [?]

GO:0008168; Molecular function:methyltransferase activity
GO:0008033; Biological process:tRNA processing

Cross-references [?]

Pfam PF02676; TYW3; 1;

Features [?]

Additional information [?]

Size range 180-250 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Function annotated by similarity to eukaryotic TYW3.

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