HAMAP rule MF_00266
General rule information
[?]
| Accession | MF_00266 |
| Dates | 1-JUN-2001 (Created)
2-SEP-2024 (Last updated, Version 23) |
| Name | TYW3_archaea |
| Scope(s) |
Archaea |
| Template(s) | P53177 (TYW3_YEAST); [ Recover all ] |
| Triggered by |
HAMAP; MF_00266 (Get profile general information and statistics) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier | TYW3 |
| Protein name | RecName: Full=tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase; EC=2.1.1.282; AltName: Full=tRNA wyosine derivatives biosynthesis protein Taw3; |
| Gene name | Name=taw3; |
Comments
[?]
| FUNCTION | S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72. |
| CATALYTIC ACTIVITY | Reaction=4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3- carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+); Xref=Rhea:RHEA:36635, Rhea:RHEA-COMP:10378, Rhea:RHEA- COMP:10379, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:73543, ChEBI:CHEBI:73550; EC=2.1.1.282; |
| SIMILARITY | Belongs to the TYW3 family. |
Keywords
[?]
Gene Ontology
[?]
| GO:0008168; Molecular function:methyltransferase activity |
| GO:0008033; Biological process:tRNA processing |
Cross-references
[?]
| Pfam | PF02676; TYW3; 1; |
Features
[?]
Additional information
[?]
| Size range | 180-250 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Function annotated by similarity to eukaryotic TYW3. |