HAMAP rule MF_00268
General rule information
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Accession | MF_00268 |
Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 52) |
Name | RecA |
Scope | Bacteria |
Templates | P0A7G6 (RECA_ECOLI); P9WHJ3 (RECA_MYCTU): [Recover all] |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the RecA family. |
Keywords
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Cytoplasm
DNA damage
DNA recombination
DNA repair
SOS response
ATP-binding
Nucleotide-binding
DNA-binding
DNA damage
DNA recombination
DNA repair
SOS response
ATP-binding
Nucleotide-binding
DNA-binding
Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0003697; Molecular function: single-stranded DNA binding.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0003697; Molecular function: single-stranded DNA binding.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Pfam | PF00154; RecA; 1; |
PRINTS | PR00142; RECA; 1; |
NCBIfam | TIGR02012; Tigrfam_recA; 1; |
PROSITE | PS00321; RECA_1; 1; |
PS50162; RECA_2; 1; | |
PS50163; RECA_3; 1; |
Features
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From: RECA_ECOLI (P0A7G6) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 67 | 74 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | G-x-E-S-[GS]-G-K-T |
Additional information
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Size range | 329-414 amino acids |
Related rules | None |
Fusion | None |
Comments | Inteins deleted in MYCLE and MYCTU |