HAMAP rule MF_00268
General rule information
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| Accession | MF_00268 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 52) |
| Name | RecA |
| Scope(s) |
Bacteria |
| Template(s) | P0A7G6 (RECA_ECOLI); P9WHJ3 (RECA_MYCTU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00268 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RECA |
| Protein name | RecName: Full=Protein RecA; AltName: Full=Recombinase A; |
| Gene name | Name=recA; |
Comments
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| FUNCTION | Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the RecA family. |
Keywords
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| Cytoplasm |
| DNA damage |
| DNA recombination |
| DNA repair |
| SOS response |
| ATP-binding |
| Nucleotide-binding |
| DNA-binding |
Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0003684; Molecular function:damaged DNA binding |
| GO:0008094; Molecular function:ATP-dependent activity, acting on DNA |
| GO:0003697; Molecular function:single-stranded DNA binding |
| GO:0006310; Biological process:DNA recombination |
| GO:0006281; Biological process:DNA repair |
| GO:0006974; Biological process:DNA damage response |
| GO:0009432; Biological process:SOS response |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00154; RecA; 1; |
| PRINTS | PR00142; RECA; 1; |
| NCBIfam | TIGR02012; Tigrfam_recA; 1; |
| PROSITE | PS00321; RECA_1; 1; |
| PROSITE | PS50162; RECA_2; 1; |
| PROSITE | PS50163; RECA_3; 1; |
Features
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| From: RECA_ECOLI (P0A7G6) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 67 | 74 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
G-x-E-S-[GS]-G-K-T | ||||||||
Additional information
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| Size range | 329-414 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Inteins deleted in MYCLE and MYCTU |