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HAMAP rule MF_00268

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General rule information [?]

Accession MF_00268
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 52)
Name RecA
Scope(s) Bacteria
Template(s) P0A7G6 (RECA_ECOLI); P9WHJ3 (RECA_MYCTU); [ Recover all ]
Triggered by HAMAP; MF_00268 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RECA
Protein name RecName: Full=Protein RecA;
AltName: Full=Recombinase A;
Gene name Name=recA;

Comments [?]

FUNCTIONCan catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
SIMILARITYBelongs to the RecA family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0003684; Molecular function:damaged DNA binding
GO:0008094; Molecular function:ATP-dependent activity, acting on DNA
GO:0003697; Molecular function:single-stranded DNA binding
GO:0006310; Biological process:DNA recombination
GO:0006281; Biological process:DNA repair
GO:0006974; Biological process:DNA damage response
GO:0009432; Biological process:SOS response
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00154; RecA; 1;
PRINTS PR00142; RECA; 1;
NCBIfam TIGR02012; Tigrfam_recA; 1;
PROSITE PS00321; RECA_1; 1;
PROSITE PS50162; RECA_2; 1;
PROSITE PS50163; RECA_3; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 67 74 /ligand="ATP"

Additional information [?]

Size range 329-414 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Inteins deleted in MYCLE and MYCTU

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