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HAMAP rule MF_00268

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General rule information [?]

Accession MF_00268
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 52)
Name RecA
Templates P0A7G6 (RECA_ECOLI); P9WHJ3 (RECA_MYCTU): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Protein RecA;
AltName: Full=Recombinase A;
Gene name

Comments [?]

Function Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Subcellular location Cytoplasm.
Similarity Belongs to the RecA family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0003697; Molecular function: single-stranded DNA binding.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00154; RecA; 1;
PRINTS PR00142; RECA; 1;
NCBIfam TIGR02012; Tigrfam_recA; 1;
PROSITE PS00321; RECA_1; 1;
PS50162; RECA_2; 1;
PS50163; RECA_3; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
BINDING     67     74       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-x-E-S-[GS]-G-K-T  

Additional information [?]

Size range 329-414 amino acids
Related rules None
Fusion None
Comments Inteins deleted in MYCLE and MYCTU