HAMAP rule MF_00268

General rule information [?]

Accession	MF_00268
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 52)

Name

RecA

Scope

Bacteria

Templates

P0A7G6 (RECA_ECOLI); P9WHJ3 (RECA_MYCTU): [Recover all]

Triggered by

HAMAP; MF_00268 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RECA

Protein name

RecName:		Full=Protein RecA;
AltName:		Full=Recombinase A;

Gene name

recA

Comments [?]

Function	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Subcellular location	Cytoplasm.
Similarity	Belongs to the RecA family.

Keywords [?]

Cytoplasm
DNA damage
DNA recombination
DNA repair
SOS response
ATP-binding
Nucleotide-binding
DNA-binding

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0003697; Molecular function: single-stranded DNA binding.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.
GO:0009432; Biological process: SOS response.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF00154; RecA; 1;
PRINTS	PR00142; RECA; 1;
NCBIfam	TIGR02012; Tigrfam_recA; 1;
PROSITE	PS00321; RECA_1; 1;
	PS50162; RECA_2; 1;
	PS50163; RECA_3; 1;

Features [?]

From: RECA_ECOLI (P0A7G6)

Key From To Description Tag Condition FTGroup

BINDING 67 74 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 G-x-E-S-[GS]-G-K-T

Additional information [?]

Size range	329-414 amino acids
Related rules	None
Fusion	None
Comments	Inteins deleted in MYCLE and MYCTU

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