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HAMAP rule MF_00283

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General rule information [?]

Accession MF_00283
Dates 1-JUN-2001 (Created)
19-NOV-2022 (Last updated, Version 44)
Name Phe_tRNA_synth_beta1
Scope
Bacteria
Plastid
Template P27002 (SYFB_THETH)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SYFB
case not <OG:Chloroplast>
Protein name
RecName: Full=Phenylalanine--tRNA ligase beta subunit;
EC 6.1.1.20;
AltName: Full=Phenylalanyl-tRNA synthetase beta subunit;
Short=PheRS;
else case <OG:Chloroplast>
Protein name
RecName: Full=Phenylalanine--tRNA ligase beta subunit, chloroplastic;
EC 6.1.1.20;
AltName: Full=Phenylalanyl-tRNA synthetase beta subunit;
Short=PheRS;
end case
Gene name
pheT

Comments [?]

Catalytic activity RHEA:19413: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)
EC 6.1.1.20
Cofactor Mg(2+)
Note: Binds 2 magnesium ions per tetramer.
Subunit Tetramer of two alpha and two beta subunits.
case <OC:Bacteria>
Subcellular location Cytoplasm.
else case <OG:Chloroplast>
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.

Keywords [?]

case <OC:Bacteria>
Cytoplasm
end case
Aminoacyl-tRNA synthetase
Protein biosynthesis
Ligase
ATP-binding
Nucleotide-binding
Magnesium
Metal-binding

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0004826; Molecular function: phenylalanine-tRNA ligase activity.
GO:0006432; Biological process: phenylalanyl-tRNA aminoacylation.
case <OC:Bacteria>
GO:0005737; Cellular component: cytoplasm.
else case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF01588; tRNA_bind; 1;
TIGRFAMs TIGR00471; PheT_arch; 1;
TIGR00472; PheT_bact; 1;
PROSITE PS51483; B5; 1; trigger=PRU00816;
PS50886; TRBD; 0-1; trigger=PRU00209;
PS51447; FDX_ACB; 0-1; trigger=PRU00778;

Features [?]

From: SYFB_THETH (P27002)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     452     452       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_note="shared with alpha subunit     D  
BINDING     458     458       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_note="shared with alpha subunit     D  
BINDING     461     461       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_note="shared with alpha subunit     E  
BINDING     462     462       /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_note="shared with alpha subunit     [ED]  

Additional information [?]

Size range 706-869 amino acids
Related rules None
Fusion None


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