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HAMAP rule MF_00286

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General rule information [?]

Accession MF_00286
Dates 1-JUN-2001 (Created)
3-JUN-2021 (Last updated, Version 46)
Name DsbB
Scope(s) Bacteria
Template(s) P0A6M2 (DSBB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00286 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DSBB
Protein name RecName: Full=Disulfide bond formation protein B;
AltName: Full=Disulfide oxidoreductase;
Gene name Name=dsbB;

Comments [?]

FUNCTIONRequired for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the DsbB family.

Keywords [?]

Gene Ontology [?]

GO:0009055; Molecular function:electron transfer activity
GO:0015035; Molecular function:protein-disulfide reductase activity
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF02600; DsbB; 1;

Features [?]

Key From To Description Tag Condition FTGroup
TOPO_DOM Nter 14 /note="Cytoplasmic"
TRANSMEM 15 31 /note="Helical"
TOPO_DOM 32 49 /note="Periplasmic"
TRANSMEM 50 65 /note="Helical"
TOPO_DOM 66 71 /note="Cytoplasmic"
TRANSMEM 72 89 /note="Helical"
TOPO_DOM 90 144 /note="Periplasmic"
TRANSMEM 145 163 /note="Helical"
TOPO_DOM 164 Cter /note="Cytoplasmic"
DISULFID 41 44 /note="Redox-active" C-x-x-C
DISULFID 104 130 /note="Redox-active" C-x*-C

Additional information [?]

Size range 158-185 amino acids
Related rules MF_00287
Fusion Nter: None Cter: None

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