HAMAP rule MF_00286
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00286 |
| Accession | MF_00286 |
| Dates | 28-FEB-2005 (Created)
03-JUN-2021 (Last updated, Version 34) |
| Name | DsbB |
| Scope(s) |
Bacteria |
| Template(s) | P0A6M2; [ Recover all ] |
| Triggered by |
HAMAP; MF_00286 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | DSBB |
| Protein name | RecName: Full=Disulfide bond formation protein B; AltName: Full=Disulfide oxidoreductase; |
| Gene name | Name=dsbB; |
Comments
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| FUNCTION | Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein. |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Multi-pass membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the DsbB family. |
Keywords
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| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Disulfide bond | |
| Oxidoreductase | |
| Redox-active center | |
| Transport | |
| Electron transport | |
| Chaperone | |
| Transmembrane | |
| Membrane | |
| Transmembrane helix | |
Gene Ontology
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| GO:0009055; Molecular function:electron transfer activity |
| GO:0015035; Molecular function:protein-disulfide reductase activity |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF02600; DsbB; 1; |
Features
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| From: DSBB_ECOLI (P0A6M2) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| TOPO_DOM | Nter | 14 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 15 | 31 | /note="Helical" | |||||||||
| TOPO_DOM | 32 | 49 | /note="Periplasmic" | |||||||||
| TRANSMEM | 50 | 65 | /note="Helical" | |||||||||
| TOPO_DOM | 66 | 71 | /note="Cytoplasmic" | |||||||||
| TRANSMEM | 72 | 89 | /note="Helical" | |||||||||
| TOPO_DOM | 90 | 144 | /note="Periplasmic" | |||||||||
| TRANSMEM | 145 | 163 | /note="Helical" | |||||||||
| TOPO_DOM | 164 | Cter | /note="Cytoplasmic" | |||||||||
| DISULFID | 41 | 44 | /note="Redox-active" | C-x-x-C | ||||||||
| DISULFID | 104 | 130 | /note="Redox-active" | C-x*-C | ||||||||
Additional information
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| Size range | 158-185 amino acids |
| Related rules |
MF_00287 MF_01311 |
| Fusion | Nter: None Cter: None |