HAMAP rule MF_00298

General rule information [?]

Accession	MF_00298
Dates	1-JUN-2001 (Created) 18-NOV-2019 (Last updated, Version 25)

Name	Nudix_RppH

Scope

Bacteria

Templates

P0A776 (RPPH_ECOLI); Q9ZDT9 (RPPH_RICPR): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RPPH

Protein name

RecName:		Full=RNA pyrophosphohydrolase;
		EC 3.6.1.-;
AltName:		Full=(Di)nucleoside polyphosphate hydrolase;

Gene name

rppH, nudH

Comments [?]

Function	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
Cofactor	a divalent metal cation
Similarity	Belongs to the Nudix hydrolase family. RppH subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016818; Molecular function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides.

Cross-references [?]

Features [?]

From: RPPH_ECOLI (P0A776)

Key From To Description Tag Condition FTGroup

MOTIF 38 59 Nudix box

Additional information [?]

Size range	155-238 amino acids
Related rules	None
Fusion	Nter: <Unknown>; Cter: None
Comments	Unknown N-terminal domain in COXBU