HAMAP rule MF_00301
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00301 |
| Accession | MF_00301 |
| Dates | 28-FEB-2005 (Created)
02-SEP-2024 (Last updated, Version 18) |
| Name | Homoser_kinase_2 |
| Scope(s) |
Bacteria |
| Template(s) | P29364; Q9RAM6; [ Recover all ] |
| Triggered by |
HAMAP; MF_00301 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | KHSE |
| Protein name | RecName: Full=Homoserine kinase; Short=HK; Short=HSK; EC=2.7.1.39; |
| Gene name | Name=thrB; |
Comments
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| CATALYTIC ACTIVITY | Reaction=L-homoserine + ATP = O-phospho-L-homoserine + ADP + H(+); Xref=Rhea:RHEA:13985, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57476, ChEBI:CHEBI:57590, ChEBI:CHEBI:456216; EC=2.7.1.39; |
| PATHWAY | Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. |
| SIMILARITY | Belongs to the pseudomonas-type ThrB family. |
Keywords
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Gene Ontology
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| GO:0004413; Molecular function:homoserine kinase activity |
| GO:0009088; Biological process:threonine biosynthetic process |
Cross-references
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Features
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Additional information
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| Size range | 305-334 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Other species have a classical-type thrB |