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HAMAP rule MF_00308

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General rule information [?]

Accession MF_00308
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 24)
Name PfdA
Scope
Archaea
Bacteria; Aquificae
Template O27646 (PFDA_METTH)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PFDA
case <OC:Archaea>
Protein name
RecName: Full=Prefoldin subunit alpha;
AltName: Full=GimC subunit alpha;
Gene name
pfdA
end case
case <OC:Bacteria>
Protein name
RecName: Full=Putative prefoldin subunit alpha;
end case

Comments [?]

case <OC:Archaea>
Function Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
Subunit Heterohexamer of two alpha and four beta subunits.
end case
case <OC:Bacteria>
Function Molecular chaperone capable of stabilizing a range of proteins.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the prefoldin alpha subunit family.

Keywords [?]

Cytoplasm
Chaperone

Gene Ontology [?]

GO:0051082; Molecular function: unfolded protein binding.
GO:0006457; Biological process: protein folding.
GO:0016272; Cellular component: prefoldin complex.

Cross-references [?]

Pfam PF02996; Prefoldin; 1;
NCBIfam TIGR00293; TIGR00293; 1;

Additional information [?]

Size range 129-160 amino acids
Related rules None
Fusion None


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