HAMAP rule MF_00308

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00308
Accession	MF_00308
Dates	28-FEB-2005 (Created) 14-MAY-2024 (Last updated, Version 20)
Name	PfdA
Scope(s)	Archaea Bacteria Aquificia
Template(s)	O27646; [ Recover all ]
Triggered by	HAMAP; MF_00308 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PFDA
case <OC:Archaea>
Protein name	RecName: Full=Prefoldin subunit alpha; AltName: Full=GimC subunit alpha;
Gene name	Name=pfdA;
end case
case <OC:Bacteria>
Protein name	RecName: Full=Putative prefoldin subunit alpha;
end case

Comments [?]

case <OC:Archaea>
FUNCTION	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
SUBUNIT	Heterohexamer of two alpha and four beta subunits.
end case
case <OC:Bacteria>
FUNCTION	Molecular chaperone capable of stabilizing a range of proteins.
end case
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the prefoldin alpha subunit family.

Keywords [?]

Gene Ontology [?]

GO:0051082; Molecular function:unfolded protein binding

GO:0006457; Biological process:protein folding

GO:0016272; Cellular component:prefoldin complex

Cross-references [?]

Pfam	PF02996; Prefoldin; 1;
NCBIfam	TIGR00293; TIGR00293; 1;

Features [?]

Additional information [?]