HAMAP rule MF_00309

General rule information [?]

Accession	MF_00309
Dates	1-JUN-2001 (Created) 2-SEP-2024 (Last updated, Version 36)
Name	ATP_synth_A_arch
Scope(s)	Bacteria Archaea
Template(s)	Q48332 (VATA_HALVD); [ Recover all ]
Triggered by	HAMAP; MF_00309 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	VATA
Protein name	RecName: Full=V-type ATP synthase alpha chain; EC=7.1.2.2; AltName: Full=V-ATPase subunit A;
Gene name	Name=atpA;

Comments [?]

case <OC:Archaea>
FUNCTION	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.
end case
case <OC:Bacteria>
FUNCTION	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.
end case
CATALYTIC ACTIVITY	Reaction=ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out); Xref=Rhea:RHEA:57720, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.2;
SIMILARITY	Belongs to the ATPase alpha/beta chains family.

Keywords [?]

<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>
ATP synthesis
Nucleotide-binding
Transport
Ion transport
Hydrogen ion transport
ATP-binding

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0046933; Molecular function:proton-transporting ATP synthase activity, rotational mechanism

GO:0042777; Biological process:proton motive force-driven plasma membrane ATP synthesis

Cross-references [?]

Features [?]

From: VATA_METJA (Q57670)

Key

From

Description

Tag

Condition

FTGroup

BINDING

234

241

/ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"

G-x-F-G-[STA]-G-K-T

Additional information [?]

Size range	570-605 amino acids
Related rules	MF_00310
Fusion	Nter: None Cter: None
Comments	Inteins deleted in PYRAB, PYRHO and THEAC