HAMAP rule MF_00309
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00309 |
| Accession | MF_00309 |
| Dates | 28-FEB-2005 (Created)
28-NOV-2024 (Last updated, Version 28) |
| Name | ATP_synth_A_arch |
| Scope(s) |
Bacteria Archaea |
| Template(s) | Q48332; Q57670; [ Recover all ] |
| Triggered by |
HAMAP; MF_00309 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Archaea> | |
| Identifier | AATA |
| Protein name | RecName: Full=A-type ATP synthase subunit A; EC=7.1.2.2; |
| end case | |
| case <OC:Bacteria> | |
| Identifier | VATA |
| Protein name | RecName: Full=V-type ATP synthase alpha chain; EC=7.1.2.2; AltName: Full=V-ATPase subunit A; |
| end case | |
| Gene name | Name=atpA; |
Comments
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| case <OC:Archaea> | |
| FUNCTION | Component of the A-type ATP synthase that produces ATP from ADP in the presence of a proton gradient across the membrane. The A chain is the catalytic subunit. |
| end case | |
| case <OC:Bacteria> | |
| FUNCTION | Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. |
| end case | |
| CATALYTIC ACTIVITY | Reaction=ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out); Xref=Rhea:RHEA:57720, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.2; |
| case <OC:Archaea> | |
| SUBUNIT | Has multiple subunits with at least A(3), B(3), C, D, E, F, H, I and proteolipid K(x). |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
| end case | |
| SIMILARITY | Belongs to the ATPase alpha/beta chains family. |
Keywords
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| Translocase | |
| ATP synthesis | |
| Nucleotide-binding | |
| Transport | |
| Ion transport | |
| Hydrogen ion transport | |
| ATP-binding | |
| case <OC:Archaea> | |
| Cell membrane | |
| Membrane | |
| end case | |
Gene Ontology
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| GO:0005524; Molecular function:ATP binding | |
| GO:0046933; Molecular function:proton-transporting ATP synthase activity, rotational mechanism | |
| GO:0042777; Biological process:proton motive force-driven plasma membrane ATP synthesis | |
| case <OCellular component:Archaea> | |
| GO:0005886; Cellular component:plasma membrane | |
| end case | |
Cross-references
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| Pfam | PF00006; ATP-synt_ab; 1; |
| Pfam | PF00306; ATP-synt_ab_C; 1; |
| NCBIfam | TIGR01043; ATP_syn_A_arch; 1; |
| PROSITE | PS00152; ATPASE_ALPHA_BETA; 1; |
Features
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| From: AATA_METJA (Q57670) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 234 | 241 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
G-x-F-G-[STA]-G-K-T | ||||||||
Additional information
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| Size range | 570-605 amino acids |
| Related rules |
MF_00310 |
| Fusion | Nter: None Cter: None |
| Comments | Inteins deleted in PYRAB, PYRHO and THEAC |