HAMAP rule MF_00313
General rule information
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| Accession | MF_00313 |
| Dates | 1-JUN-2001 (Created) 17-JAN-2023 (Last updated, Version 23) |
| Name | Glutaminase |
| Scope | Bacteria |
| Templates | O87405 (GLSA_RHIEC); O31465 (GLSA1_BACSU): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Catalytic activity | RHEA:15889: H2O + L-glutamine = L-glutamate + NH4(+)
EC 3.5.1.2 |
| Subunit | Homotetramer. |
| Similarity | Belongs to the glutaminase family. |
Keywords
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case <FT:1>
end case
Gene Ontology
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GO:0004359; Molecular function: glutaminase activity.
Cross-references
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Features
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| From: GLSA1_BACSU (O31465) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING (Optional) | 74 | 74 | /ligand="substrate | S | ||||||||
| BINDING (Optional) | 126 | 126 | /ligand="substrate | N | ||||||||
| BINDING (Optional) | 170 | 170 | /ligand="substrate | E | ||||||||
| BINDING (Optional) | 177 | 177 | /ligand="substrate | N | ||||||||
| BINDING (Optional) | 201 | 201 | /ligand="substrate | Y | ||||||||
| BINDING (Optional) | 253 | 253 | /ligand="substrate | Y | ||||||||
| BINDING (Optional) | 271 | 271 | /ligand="substrate | V | ||||||||
case <OC:Escherichia> or <OC:Shigella>
| From: GLSA1_ECOLI (P77454) | ||||||||||||
| MOD_RES | 294 | 294 | N6-acetyllysine | K | ||||||||
end case
Additional information
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| Size range | 302-340 amino acids |
| Related rules | None |
| Fusion | Nter: None; Cter: <STAS domain>, <cyclic nucleotide-binding domain> |
| Comments | Possible wrong start in SYNY3 and YERPE |