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HAMAP rule MF_00313

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General rule information [?]

Accession MF_00313
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 24)
Name Glutaminase
Scope(s) Bacteria
Template(s) O87405 (GLSA_RHIEC); O31465 (GLSA1_BACSU); [ Recover all ]
Triggered by HAMAP; MF_00313 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GLSA
Protein name RecName: Full=Glutaminase;
Gene name Name=glsA;

Comments [?]

CATALYTIC ACTIVITY Reaction=H2O + L-glutamine = L-glutamate + NH4(+); Xref=Rhea:RHEA:15889, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29985, ChEBI:CHEBI:58359; EC=;
SIMILARITYBelongs to the glutaminase family.

Keywords [?]

case <FT:1>
end case

Gene Ontology [?]

GO:0004359; Molecular function:glutaminase activity

Cross-references [?]

Pfam PF04960; Glutaminase; 1;
NCBIfam TIGR03814; Gln_ase; 1;

Features [?]

From: GLSA1_BACSU (O31465)
Key From To Description Tag Condition FTGroup
BINDING 74 74 /ligand="substrate" S
BINDING 126 126 /ligand="substrate" N
BINDING 170 170 /ligand="substrate" E
BINDING 177 177 /ligand="substrate" N
BINDING 201 201 /ligand="substrate" Y
BINDING 253 253 /ligand="substrate" Y
BINDING 271 271 /ligand="substrate" V
From: GLSA1_ECOLI (P77454)
Key From To Description Tag Condition FTGroup
case <OC:Escherichia> or <OC:Shigella>
MOD_RES 294 294 /note="N6-acetyllysine" K
end case

Additional information [?]

Size range 302-340 amino acids
Related rules None
Fusion Nter: None Cter: <STAS domain>; <cyclic nucleotide-binding domain>
Comments Possible wrong start in SYNY3 and YERPE

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