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HAMAP rule MF_00313

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General rule information [?]

Accession MF_00313
Dates 1-JUN-2001 (Created)
17-JAN-2023 (Last updated, Version 23)
Name Glutaminase
Templates O87405 (GLSA_RHIEC); O31465 (GLSA1_BACSU): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Glutaminase;
Gene name

Comments [?]

Catalytic activity RHEA:15889: H2O + L-glutamine = L-glutamate + NH4(+)
Subunit Homotetramer.
Similarity Belongs to the glutaminase family.

Keywords [?]

case <FT:1>
end case

Gene Ontology [?]

GO:0004359; Molecular function: glutaminase activity.

Cross-references [?]

Pfam PF04960; Glutaminase; 1;
TIGRFAMs TIGR03814; Gln_ase; 1;

Features [?]

From: GLSA1_BACSU (O31465)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     74     74       /ligand="substrate     S  
BINDING (Optional)     126     126       /ligand="substrate     N  
BINDING (Optional)     170     170       /ligand="substrate     E  
BINDING (Optional)     177     177       /ligand="substrate     N  
BINDING (Optional)     201     201       /ligand="substrate     Y  
BINDING (Optional)     253     253       /ligand="substrate     Y  
BINDING (Optional)     271     271       /ligand="substrate     V  
case <OC:Escherichia> or <OC:Shigella>
From: GLSA1_ECOLI (P77454)
MOD_RES     294     294       N6-acetyllysine     K  
end case

Additional information [?]

Size range 302-340 amino acids
Related rules None
Fusion Nter: None; Cter: <STAS domain>, <cyclic nucleotide-binding domain>
Comments Possible wrong start in SYNY3 and YERPE