Home  |  Contact
Annotation rule MF_00317
Send feedback

General rule information [?]

Accession MF_00317
Dates 1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 18)
Name DNApol_clamp_arch
Scope
Archaea
Templates O73947 (PCNA_PYRFU); P57765 (PCNA3_SACS2); P57766 (PCNA1_SACS2); Q97Z84 (PCNA2_SACS2); Q975N2 (PCNA1_SULTO); Q975M2 (PCNA2_SULTO); Q973F5 (PCNA3_SULTO): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PCNA
Protein name
RecName: Full=DNA polymerase sliding clamp;
AltName: Full=Proliferating cell nuclear antigen homolog;
Short=PCNA;
Gene name
pcn

Comments [?]

Function Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
Subunit Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
Similarity Belongs to the PCNA family.

Keywords [?]


Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
GO:0030337; Molecular function: DNA polymerase processivity factor activity.
GO:0006275; Biological process: regulation of DNA replication.

Cross-references [?]

Pfam PF02747; PCNA_C; 1;
PF00705; PCNA_N; 1;
PRINTS PR00339; PCNACYCLIN; 1;
TIGRFAMs TIGR00590; Pcna; 1;
PROSITE PS01251; PCNA_1; 1;
PS00293; PCNA_2; 1;

Additional information [?]

Size range 244-256 amino acids
Related rules None
Fusion None
Comments Some Archaea have up to 3 copies.