HAMAP rule MF_00319
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00319 |
| Accession | MF_00319 |
| Dates | 28-FEB-2005 (Created)
14-MAY-2024 (Last updated, Version 29) |
| Name | Cdh |
| Scope(s) |
Bacteria |
| Template(s) | P06282; [ Recover all ] |
| Triggered by |
HAMAP; MF_00319 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | CDH |
| Protein name | RecName: Full=CDP-diacylglycerol pyrophosphatase; EC=3.6.1.26; AltName: Full=CDP-diacylglycerol phosphatidylhydrolase; AltName: Full=CDP-diglyceride hydrolase; |
| Gene name | Name=cdh; |
Comments
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| CATALYTIC ACTIVITY | Reaction=a CDP-1,2-diacyl-sn-glycerol + H2O = a 1,2-diacyl-sn-glycero- 3-phosphate + CMP + 2 H(+); Xref=Rhea:RHEA:15221, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:58332, ChEBI:CHEBI:58608, ChEBI:CHEBI:60377; EC=3.6.1.26; |
| PATHWAY | Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1. |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Single-pass membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass membrane protein. |
| end case | |
| SIMILARITY | Belongs to the Cdh family. |
Keywords
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| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Hydrolase | |
| Lipid biosynthesis | |
| Lipid metabolism | |
| Membrane | |
| Phospholipid biosynthesis | |
| Phospholipid metabolism | |
| Transmembrane | |
| Transmembrane helix | |
Gene Ontology
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| GO:0008715; Molecular function:CDP-diacylglycerol diphosphatase activity |
| GO:0046342; Biological process:CDP-diacylglycerol catabolic process |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF02611; CDH; 1; |
| NCBIfam | TIGR00672; Cdh; 1; |
| General | Transmembrane; -; 1; |
Features
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Additional information
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| Size range | 244-268 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |