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HAMAP rule MF_00325

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General rule information [?]

Accession MF_00325
Dates 1-JUN-2001 (Created)
3-MAY-2022 (Last updated, Version 25)
Name DNApol_II_A_arch
Template P81412 (DP2S_PYRFU)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=DNA polymerase II small subunit;
Short=Pol II;
AltName: Full=Exodeoxyribonuclease small subunit;
Gene name

Comments [?]

Function Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
Catalytic activity RHEA:22508: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
Reaction=Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.; EC=;
Subunit Heterodimer of a large subunit and a small subunit.
Similarity Belongs to the DNA polymerase delta/II small subunit family.

Keywords [?]

Gene Ontology [?]

GO:0008408; Molecular function: 3'-5' exonuclease activity.
GO:0003677; Molecular function: DNA binding.
GO:0003887; Molecular function: DNA-directed DNA polymerase activity.
GO:0000738; Biological process: DNA catabolic process, exonucleolytic.
GO:0006261; Biological process: DNA-templated DNA replication.

Cross-references [?]

Pfam PF01336; tRNA_anti; 1;

Additional information [?]

Size range 370-735 amino acids
Related rules None
Fusion None