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Annotation rule MF_00345 |
Accession | MF_00345 |
Dates | 1-JUN-2001 (Created) 26-SEP-2014 (Last updated, Version 29) |
Name | GMP_synthase_B |
Scope | Archaea |
Template | P04079 (GUAA_ECOLI) |
Triggered by |
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Function | Catalyzes the synthesis of GMP from XMP. |
Catalytic activity | ATP + XMP + L-glutamine + H(2)O = AMP + diphosphate + GMP + L-glutamate. |
Pathway | Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1. |
Subunit | Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B). |
Pfam | PF00958; GMP_synt_C; 1; |
TIGRFAMs | TIGR00884; GuaA_Cterm; 1; |
PROSITE | PS51553; GMPS_ATP_PPASE; 1; trigger=PRU00886; |
Size range | 303-370 amino acids |
Related rules | MF_00344 (GUAA supersedes the current rule) |
Fusion | None |
Comments | Sequences from AERPE and PYRAE are like that of Eubacteria composed of two domains, while other archaea have separate proteins that correspond to each domain |