HAMAP rule MF_00348
General rule information
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| Accession | MF_00348 |
| Dates | 1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 28) |
| Name | RadA_arch |
| Scope | Archaea |
| Templates | O74036 (RADA_PYRFU); Q9UWR5 (RADA_PYRIL); Q55075 (RADA_SACS2): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. |
| Similarity | Belongs to the eukaryotic RecA-like protein family. |
Keywords
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Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.
Cross-references
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| PRINTS | PR00142; RECA; 1; |
| NCBIfam | TIGR02236; recomb_radA; 1; |
| PROSITE | PS50162; RECA_2; 1; |
| PS50163; RECA_3; 1; |
Features
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| From: RADA_METJA (Q49593) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 136 | 143 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 | G-x-x-G-[AS]-G-K-[ST] | ||||||||
Additional information
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| Size range | 305-410 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | Intein in some members. Not a homolog of the bacterial RadA protein. |