HAMAP rule MF_00348

Accession	MF_00348
Dates	1-JUN-2001 (Created) 7-FEB-2023 (Last updated, Version 27)

Name

RadA_arch

Scope

Archaea

Templates

O74036 (RADA_PYRFU); Q9UWR5 (RADA_PYRIL); Q55075 (RADA_SACS2): [Recover all]

Triggered by

HAMAP; MF_00348 (Get profile general information and statistics)

Identifier

RADA

Protein name

RecName: Full=DNA repair and recombination protein RadA;

Gene name

radA

Function	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
Similarity	Belongs to the eukaryotic RecA-like protein family.

DNA damage
DNA recombination
ATP-binding
Nucleotide-binding
DNA-binding

GO:0005524; Molecular function: ATP binding.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.

PRINTS	PR00142; RECA; 1;
TIGRFAMs	TIGR02236; recomb_radA; 1;
PROSITE	PS50162; RECA_2; 1;
	PS50163; RECA_3; 1;

From: RADA_METJA (Q49593)

Key

From

To

Description

Tag

Condition

FTGroup

BINDING

136

143

/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616

G-x-x-G-[AS]-G-K-[ST]

Size range	305-410 amino acids
Related rules	None
Fusion	None
Comments	Intein in some members. Not a homolog of the bacterial RadA protein.

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