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HAMAP rule MF_00348

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General rule information [?]

Accession MF_00348
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 28)
Name RadA_arch
Scope
Archaea
Templates O74036 (RADA_PYRFU); Q9UWR5 (RADA_PYRIL); Q55075 (RADA_SACS2): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RADA
Protein name
RecName: Full=DNA repair and recombination protein RadA;
Gene name
radA

Comments [?]

Function Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
Similarity Belongs to the eukaryotic RecA-like protein family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003684; Molecular function: damaged DNA binding.
GO:0008094; Molecular function: ATP-dependent activity, acting on DNA.
GO:0006310; Biological process: DNA recombination.
GO:0006281; Biological process: DNA repair.
GO:0006974; Biological process: DNA damage response.

Cross-references [?]

PRINTS PR00142; RECA; 1;
NCBIfam TIGR02236; recomb_radA; 1;
PROSITE PS50162; RECA_2; 1;
PS50163; RECA_3; 1;

Features [?]

From: RADA_METJA (Q49593)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     136     143       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-x-x-G-[AS]-G-K-[ST]  

Additional information [?]

Size range 305-410 amino acids
Related rules None
Fusion None
Comments Intein in some members. Not a homolog of the bacterial RadA protein.