 |
|
| Annotation rule MF_00368 |
General rule information
[?]
| Accession |
MF_00368 |
| Dates |
1-JUN-2001 (Created)
18-NOV-2019 (Last updated, Version 29) |
case <OC:Bacteria> or <OG:Chloroplast>
end case
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case <OC:Bacteria> and not <OC:Cyanobacteria>
| Protein name |
|
RecName:
|
Full=50S ribosomal protein L7/L12;
|
|
else case <OC:Cyanobacteria>
| Protein name |
|
RecName:
|
Full=50S ribosomal protein L7/L12;
|
|
else case <OG:Chloroplast>
| Protein name |
|
RecName:
|
Full=50S ribosomal protein L12, chloroplastic;
|
|
end case
| Function |
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. |
| Subunit |
Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. |
case <OG:Chloroplast>
| Subcellular location |
Plastid, chloroplast. |
end case
| Similarity |
Belongs to the bacterial ribosomal protein bL12 family. |
case <OG:Chloroplast>
end case
Additional information
[?]
| Size range |
118-138 amino acids |
| Related rules |
None |
| Fusion |
None |
| Comments |
Has an equivalent position and function as 50S archaeal ribosomal protein L12 or 60S acidic protein P1, but has no sequence similarities. Between 2 and 4 L12 dimers bind to L10, depending on the length of the C-terminus of L10. See PubMed:20467040. |