HAMAP rule MF_00368
General rule information
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| Accession | MF_00368 |
| Dates | 1-JUN-2001 (Created)
21-SEP-2023 (Last updated, Version 34) |
| Name | Ribosomal_bL12 |
| Scope(s) |
Bacteria Plastid |
| Template(s) | P0A7K2 (RL7_ECOLI); Q8VVE2 (RL7_THET8); P29396 (RL7_THEMA); P02394 (RL7_BACSU); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Chloroplast>
HAMAP; MF_00368 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> and not <OC:Cyanobacteriota> | |
| Identifier | RL7 |
| Protein name | RecName: Full=Large ribosomal subunit protein bL12; |
| Gene name | Name=rplL; |
| else case <OC:Cyanobacteriota> | |
| Identifier | RL7 |
| Protein name | RecName: Full=Large ribosomal subunit protein bL12; |
| Gene name | Name=rplL; Synonyms=rpl12; |
| else case <OG:Chloroplast> | |
| Identifier | RK12 |
| Protein name | RecName: Full=Large ribosomal subunit protein bL12c; |
| Gene name | Name=rpl12; |
| end case | |
Comments
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| FUNCTION | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. |
| SUBUNIT | Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the bacterial ribosomal protein bL12 family. |
Keywords
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Gene Ontology
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| GO:0006412; Biological process:translation | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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Features
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Additional information
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| Size range | 118-138 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Has an equivalent position and function as 50S archaeal ribosomal protein L12 or 60S acidic protein P1, but has no sequence similarities. Between 2 and 4 L12 dimers bind to L10, depending on the length of the C-terminus of L10. See PubMed:20467040. |