Annotation rule MF_00370
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General rule information [?]

Accession MF_00370
Dates 1-JUN-2001 (Created)
26-SEP-2014 (Last updated, Version 28)
Name Shik_kinase_arch
Scope Archaea
Template Q58835 (AROK_METJA)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
AROK
Protein name
RecName: Full=Shikimate kinase;
Short=SK;
EC=2.7.1.71;
Gene name
aroK

Comments [?]

Catalytic activity ATP + shikimate = ADP + shikimate 3-phosphate.
Pathway Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.
Subcellular location Cytoplasm.
Similarity Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.

Keywords [?]

Cytoplasm
Amino-acid biosynthesis
Aromatic amino acid biosynthesis
Transferase
Kinase
ATP-binding
Nucleotide-binding

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004765; Molecular function: shikimate kinase activity.
GO:0009073; Biological process: aromatic amino acid family biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF08544; GHMP_kinases_C; 1;
PF00288; GHMP_kinases_N; 1;
PIRSF PIRSF005758; Shikimt_kin_arch; 1;
TIGRFAMs TIGR01920; Shik_kin_archae; 1;
PROSITE PS00627; GHMP_KINASES_ATP; 1;

Features [?]

From: AROK_METJA (Q58835)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     86     96       ATP     P-x(3)-G-L-x-[GS]-S-[SA]-A  

Additional information [?]

Size range 268-294 amino acids
Related rules None
Fusion None
Comments Bacterial aroK belong to a separate family


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