HAMAP rule MF_00370
General rule information
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| Accession | MF_00370 |
| Dates | 1-JUN-2001 (Created)
12-MAR-2024 (Last updated, Version 34) |
| Name | Shik_kinase_arch |
| Scope(s) |
Archaea |
| Template(s) | Q58835 (AROK_METJA); [ Recover all ] |
| Triggered by |
HAMAP; MF_00370 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | AROK |
| Protein name | RecName: Full=Shikimate kinase; Short=SK; EC=2.7.1.71; |
| Gene name | Name=aroK; |
Comments
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| CATALYTIC ACTIVITY | Reaction=ATP + shikimate = 3-phosphoshikimate + ADP + H(+); Xref=Rhea:RHEA:13121, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:36208, ChEBI:CHEBI:145989, ChEBI:CHEBI:456216; EC=2.7.1.71; |
| PATHWAY | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily. |
Keywords
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| Cytoplasm |
| Amino-acid biosynthesis |
| Aromatic amino acid biosynthesis |
| Transferase |
| Kinase |
| ATP-binding |
| Nucleotide-binding |
Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0004765; Molecular function:shikimate kinase activity |
| GO:0009423; Biological process:chorismate biosynthetic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF08544; GHMP_kinases_C; 1; |
| Pfam | PF00288; GHMP_kinases_N; 1; |
| PIRSF | PIRSF005758; Shikimt_kin_arch; 1; |
| NCBIfam | TIGR01920; Shik_kin_archae; 1; |
| PROSITE | PS00627; GHMP_KINASES_ATP; 1; |
Features
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| From: AROK_METJA (Q58835) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 86 | 96 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
P-x(3)-G-L-x-[GS]-S-[SA]-A | ||||||||
Additional information
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| Size range | 268-294 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Bacterial aroK belong to a separate family |