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HAMAP rule MF_00370

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General rule information [?]

Accession MF_00370
Dates 1-JUN-2001 (Created)
12-MAR-2024 (Last updated, Version 34)
Name Shik_kinase_arch
Scope(s) Archaea
Template(s) Q58835 (AROK_METJA); [ Recover all ]
Triggered by HAMAP; MF_00370 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier AROK
Protein name RecName: Full=Shikimate kinase;
                 Short=SK;
                 EC=2.7.1.71;
Gene name Name=aroK;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + shikimate = 3-phosphoshikimate + ADP + H(+); Xref=Rhea:RHEA:13121, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:36208, ChEBI:CHEBI:145989, ChEBI:CHEBI:456216; EC=2.7.1.71;
PATHWAYMetabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0004765; Molecular function:shikimate kinase activity
GO:0009423; Biological process:chorismate biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF08544; GHMP_kinases_C; 1;
Pfam PF00288; GHMP_kinases_N; 1;
PIRSF PIRSF005758; Shikimt_kin_arch; 1;
NCBIfam TIGR01920; Shik_kin_archae; 1;
PROSITE PS00627; GHMP_KINASES_ATP; 1;

Features [?]

From: AROK_METJA (Q58835)
Key From To Description Tag Condition FTGroup
BINDING 86 96 /ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"
P-x(3)-G-L-x-[GS]-S-[SA]-A

Additional information [?]

Size range 268-294 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Bacterial aroK belong to a separate family



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