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HAMAP rule MF_00378

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General rule information [?]

Accession MF_00378
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 25)
Name Exonuc_7_L
Scope(s) Bacteria
Template(s) P04994 (EX7L_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00378 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier EX7L
Protein name RecName: Full=Exodeoxyribonuclease 7 large subunit;
AltName: Full=Exodeoxyribonuclease VII large subunit;
                 Short=Exonuclease VII large subunit;
Gene name Name=xseA;

Comments [?]

FUNCTIONBidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
CATALYTIC ACTIVITY Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'- direction to yield nucleoside 5'-phosphates.; EC=;
SUBUNITHeterooligomer composed of large and small subunits.
SIMILARITYBelongs to the XseA family.

Keywords [?]

Gene Ontology [?]

GO:0008855; Molecular function:exodeoxyribonuclease VII activity
GO:0006308; Biological process:DNA catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02601; Exonuc_VII_L; 1;
Pfam PF01336; tRNA_anti; 1;
NCBIfam TIGR00237; XseA; 1;

Features [?]

Additional information [?]

Size range 387-555 amino acids
Related rules None
Fusion Nter: None Cter: None

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