HAMAP rule MF_00378

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00378
Accession	MF_00378
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 25)
Name	Exonuc_7_L
Scope(s)	Bacteria
Template(s)	P04994 (EX7L_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_00378 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	EX7L
Protein name	RecName: Full=Exodeoxyribonuclease 7 large subunit; EC=3.1.11.6; AltName: Full=Exodeoxyribonuclease VII large subunit; Short=Exonuclease VII large subunit;
Gene name	Name=xseA;

Comments [?]

FUNCTION	Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
CATALYTIC ACTIVITY	Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'- direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
SUBUNIT	Heterooligomer composed of large and small subunits.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the XseA family.

Keywords [?]

Gene Ontology [?]

GO:0008855; Molecular function:exodeoxyribonuclease VII activity

GO:0006308; Biological process:DNA catabolic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]