HAMAP rule MF_00378

General rule information [?]

Accession	MF_00378
Dates	1-JUN-2001 (Created) 1-JUN-2023 (Last updated, Version 25)

Name	Exonuc_7_L

Scope

Bacteria

Template

P04994 (EX7L_ECOLI)

Triggered by

HAMAP; MF_00378 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

EX7L

Protein name

RecName:		Full=Exodeoxyribonuclease 7 large subunit;
		EC 3.1.11.6;
AltName:		Full=Exodeoxyribonuclease VII large subunit;
		Short=Exonuclease VII large subunit;

Gene name

xseA

Comments [?]

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
Catalytic activity	Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.; EC=3.1.11.6;
Subunit	Heterooligomer composed of large and small subunits.
Subcellular location	Cytoplasm.
Similarity	Belongs to the XseA family.

Keywords [?]

Cytoplasm
Hydrolase
Nuclease
Exonuclease

Gene Ontology [?]

GO:0008855; Molecular function: exodeoxyribonuclease VII activity.
GO:0006308; Biological process: DNA catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF02601; Exonuc_VII_L; 1;
	PF01336; tRNA_anti; 1;
NCBIfam	TIGR00237; XseA; 1;

Additional information [?]

Size range	387-555 amino acids
Related rules	None
Fusion	None

View rule in raw text format (no links)