HAMAP logo

HAMAP rule MF_00378

Send feedback

General rule information [?]

Accession MF_00378
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 25)
Name Exonuc_7_L
Template P04994 (EX7L_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Exodeoxyribonuclease 7 large subunit;
AltName: Full=Exodeoxyribonuclease VII large subunit;
Short=Exonuclease VII large subunit;
Gene name

Comments [?]

Function Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
Catalytic activity Reaction=Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.; EC=;
Subunit Heterooligomer composed of large and small subunits.
Subcellular location Cytoplasm.
Similarity Belongs to the XseA family.

Keywords [?]

Gene Ontology [?]

GO:0008855; Molecular function: exodeoxyribonuclease VII activity.
GO:0006308; Biological process: DNA catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02601; Exonuc_VII_L; 1;
PF01336; tRNA_anti; 1;
NCBIfam TIGR00237; XseA; 1;

Additional information [?]

Size range 387-555 amino acids
Related rules None
Fusion None