HAMAP logo

HAMAP rule MF_00390

Send feedback

General rule information [?]

Accession MF_00390
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 23)
Name Thiourid_synth_D
Bacteria; Enterobacterales
Template P45532 (TUSD_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Sulfurtransferase TusD;
EC 2.8.1.-;
AltName: Full=tRNA 2-thiouridine synthesizing protein D;
Gene name

Comments [?]

Function Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
Subunit Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
Subcellular location Cytoplasm.
Similarity Belongs to the DsrE/TusD family.

Keywords [?]

Gene Ontology [?]

GO:0016783; Molecular function: sulfurtransferase activity.
GO:0008033; Biological process: tRNA processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF02635; DrsE; 1;
NCBIfam TIGR03012; sulf_tusD_dsrE; 1;

Features [?]

From: TUSD_ECOLI (P45532)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     78     78       Cysteine persulfide intermediate     C  

Additional information [?]

Size range 128-131 amino acids
Related rules None
Fusion None