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HAMAP rule MF_00390

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General rule information [?]

Accession MF_00390
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 23)
Name Thiourid_synth_D
Scope(s) Bacteria
Template(s) P45532 (TUSD_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00390 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TUSD
Protein name RecName: Full=Sulfurtransferase TusD;
AltName: Full=tRNA 2-thiouridine synthesizing protein D;
Gene name Name=tusD;

Comments [?]

FUNCTIONPart of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
SUBUNITHeterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
SIMILARITYBelongs to the DsrE/TusD family.

Keywords [?]

Gene Ontology [?]

GO:0016783; Molecular function:sulfurtransferase activity
GO:0008033; Biological process:tRNA processing
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02635; DrsE; 1;
NCBIfam TIGR03012; sulf_tusD_dsrE; 1;

Features [?]

From: TUSD_ECOLI (P45532)
Key From To Description Tag Condition FTGroup
ACT_SITE 78 78 /note="Cysteine persulfide intermediate" C

Additional information [?]

Size range 128-131 amino acids
Related rules None
Fusion Nter: None Cter: None

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