HAMAP rule MF_00390
General rule information
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| Accession | MF_00390 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 23) |
| Name | Thiourid_synth_D |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P45532 (TUSD_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00390 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | TUSD |
| Protein name | RecName: Full=Sulfurtransferase TusD; EC=2.8.1.-; AltName: Full=tRNA 2-thiouridine synthesizing protein D; |
| Gene name | Name=tusD; |
Comments
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| FUNCTION | Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. |
| SUBUNIT | Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the DsrE/TusD family. |
Keywords
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Gene Ontology
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| GO:0016783; Molecular function:sulfurtransferase activity |
| GO:0008033; Biological process:tRNA processing |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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| From: TUSD_ECOLI (P45532) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 78 | 78 | /note="Cysteine persulfide intermediate" | C | ||||||||
Additional information
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| Size range | 128-131 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |