HAMAP rule MF_00411
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00411 |
| Accession | MF_00411 |
| Dates | 28-FEB-2005 (Created)
21-MAR-2025 (Last updated, Version 26) |
| Name | RNApol_arch_Rpo1C |
| Scope(s) |
Archaea |
| Template(s) | B0R8D3; P09847; P11514; Q03586; [ Recover all ] |
| Triggered by |
HAMAP; MF_00411 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RPO1C |
| Protein name | RecName: Full=DNA-directed RNA polymerase subunit Rpo1C; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase subunit A''; |
| Gene name | Name=rpo1C; Synonyms=rpoA2; |
Comments
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| FUNCTION | DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain. |
| CATALYTIC ACTIVITY | Reaction=RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate; Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA- COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395; EC=2.7.7.6; |
| SUBUNIT | Part of the RNA polymerase complex. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the RNA polymerase beta' chain family. |
Keywords
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Gene Ontology
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| GO:0005737; Cellular component:cytoplasm |
| GO:0003677; Molecular function:DNA binding |
| GO:0003899; Molecular function:DNA-directed RNA polymerase activity |
| GO:0006351; Biological process:DNA-templated transcription |
Cross-references
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Features
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Additional information
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| Size range | 375-510 amino acids |
| Related rules |
None |
| Fusion | Nter: <Unknown> Cter: None |
| Comments | Unknown N-terminal domain in METTH, METTL, THEAC and THEVO. Intein deleted in METJA. In Thaumarchaeota Rpo1N and Rpo1C are fused. |