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HAMAP rule MF_00425

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General rule information [?]

Accession MF_00425
Dates 13-JUL-2001 (Created)
11-JAN-2021 (Last updated, Version 25)
Name NqrA
Templates Q56586 (NQRA_VIBAL); A5F5X1 (NQRA_VIBC3): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Na(+)-translocating NADH-quinone reductase subunit A;
Short=Na(+)-NQR subunit A;
Short=Na(+)-translocating NQR subunit A;
AltName: Full=NQR complex subunit A;
AltName: Full=NQR-1 subunit A;
Gene name

Comments [?]

Function NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Catalytic activity RHEA:47748: a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)
Subunit Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
Similarity Belongs to the NqrA family.

Keywords [?]

Gene Ontology [?]

GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
GO:0006814; Biological process: sodium ion transport.

Cross-references [?]

Pfam PF05896; NQRA; 1;
TIGRFAMs TIGR01936; NqrA; 1;

Additional information [?]

Size range 400-505 amino acids
Related rules None
Fusion None