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Annotation rule MF_00426
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General rule information [?]

Accession MF_00426
Dates 16-JUL-2001 (Created)
18-NOV-2019 (Last updated, Version 43)
Name NqrB
Scope
Bacteria
Templates Q56587 (NQRB_VIBAL); A5F5X0 (NQRB_VIBC3): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
NQRB
Protein name
RecName: Full=Na(+)-translocating NADH-quinone reductase subunit B;
Short=Na(+)-NQR subunit B;
Short=Na(+)-translocating NQR subunit B;
EC 7.2.1.1;
AltName: Full=NQR complex subunit B;
AltName: Full=NQR-1 subunit B;
Gene name
nqrB

Comments [?]

Function NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Catalytic activity RHEA:47748: a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)
EC 7.2.1.1
Cofactor FMN
Subunit Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the NqrB/RnfD family.

Keywords [?]

Translocase
NAD
Ubiquinone
Transport
Ion transport
Sodium
Sodium transport
Flavoprotein
FMN
Cell membrane
Membrane
Transmembrane
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
case <FT:1>
Phosphoprotein
end case
Transmembrane helix

Gene Ontology [?]

GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
GO:0006814; Biological process: sodium ion transport.
GO:0055114; Biological process: oxidation-reduction process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF03116; NQR2_RnfD_RnfE; 1;
PIRSF PIRSF016055; NADH-UbQ_OxRdtase_B_su; 1;
TIGRFAMs TIGR01937; NqrB; 1;

Computed features [?]

General Transmembrane; -; 8-10; trigger=yes;

Features [?]

From: NQRB_VIBAL (Q56587)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     236     236       FMN phosphoryl threonine     T  

Additional information [?]

Size range 380-503 amino acids
Related rules MF_00462 (RSXD)
Fusion None


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