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Annotation rule MF_00428 |
General rule information
[?]
Accession |
MF_00428 |
Dates |
16-JUL-2001 (Created) 18-NOV-2019 (Last updated, Version 39) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Na(+)-translocating NADH-quinone reductase subunit D;
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Short=Na(+)-NQR subunit D;
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Short=Na(+)-translocating NQR subunit D;
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EC 7.2.1.1;
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AltName:
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Full=NQR complex subunit D;
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AltName:
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Full=NQR-1 subunit D;
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Function |
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. |
Catalytic activity |
RHEA:47748: a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)
EC 7.2.1.1
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Subunit |
Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity |
Belongs to the NqrDE/RnfAE family. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
GO:0006814; Biological process: sodium ion transport.
GO:0055114; Biological process: oxidation-reduction process.
GO:0005886; Cellular component: plasma membrane.
General |
Transmembrane; -; 5-7; trigger=yes; |
Additional information
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Size range |
195-254 amino acids |
Related rules |
MF_00429 (NQRE) |
Fusion |
None |