HAMAP rule MF_00442

General rule information [?]

Accession	MF_00442
Dates	29-AUG-2001 (Created) 13-NOV-2023 (Last updated, Version 33)
Name	Helicase_Hel308
Scope(s)	Archaea
Template(s)	O73946 (HELS_PYRFU); O26901 (HELS_METTH); Q974S1 (HELS_SULTO); D0KN27 (HELS_SACS9); [ Recover all ]
Triggered by	HAMAP; MF_00442 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	HELS
RecName: Full=ATP-dependent DNA helicase Hel308;<br />                  EC=<a href="https://enzyme.expasy.org/EC/5.6.2.4">5.6.2.4</a>;<br /> AltName: Full=DNA 3'-5' helicase Hel308;
Gene name	Name=hel308;

Comments [?]

FUNCTION	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
CATALYTIC ACTIVITY	Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.; EC=5.6.2.4;
CATALYTIC ACTIVITY	Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
SUBUNIT	Monomer.
SIMILARITY	Belongs to the helicase family. Hel308 subfamily.

Keywords [?]

ATP-binding
DNA-binding
<a href="https://www.uniprot.org/keywords/KW-0347">Helicase</a>
Hydrolase
Isomerase
Nucleotide-binding
DNA damage
DNA repair

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding

GO:0003677; Molecular function:DNA binding

GO:0043138; Molecular function:3'-5' DNA helicase activity

GO:0016818; Molecular function:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO:0006281; Biological process:DNA repair

Cross-references [?]

Features [?]

From: HELS_PYRFU (O73946)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="ATP"
/ligand_id="ChEBI:CHEBI:30616"

Additional information [?]