HAMAP rule MF_00442
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00442 |
| Accession | MF_00442 |
| Dates | 28-FEB-2005 (Created)
03-SEP-2024 (Last updated, Version 30) |
| Name | Helicase_Hel308 |
| Scope(s) |
Archaea |
| Template(s) | O73946; O26901; Q974S1; D0KN27; [ Recover all ] |
| Triggered by |
HAMAP; MF_00442 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HELS |
| Protein name | RecName: Full=ATP-dependent DNA helicase Hel308; EC=5.6.2.4; AltName: Full=DNA 3'-5' helicase Hel308; |
| Gene name | Name=hel308; |
Comments
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| FUNCTION | DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. |
| CATALYTIC ACTIVITY | Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.; EC=5.6.2.4; |
| CATALYTIC ACTIVITY | Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4; |
| SUBUNIT | Monomer. |
| SIMILARITY | Belongs to the helicase family. Hel308 subfamily. |
Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0003677; Molecular function:DNA binding |
| GO:0043138; Molecular function:3'-5' DNA helicase activity |
| GO:0016818; Molecular function:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0006281; Biological process:DNA repair |
Cross-references
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| Pfam | PF00270; DEAD; 1; |
| Pfam | PF00271; Helicase_C; 1; |
| Pfam | PF00633; HHH; 1; |
| PROSITE | PS51192; HELICASE_ATP_BIND_1; 1; |
| PROSITE | PS51194; HELICASE_CTER; 1; |
Features
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| From: HELS_PYRFU (O73946) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 28 | 28 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
Q | ||||||||
Additional information
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| Size range | 639-880 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Intein in some members. |