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Annotation rule MF_00470 |
General rule information
[?]
Accession |
MF_00470 |
Dates |
24-OCT-2001 (Created) 18-NOV-2019 (Last updated, Version 30) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
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Full=o-succinylbenzoate synthase;
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Short=OSB synthase;
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Short=OSBS;
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EC 4.2.1.113;
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AltName:
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Full=4-(2'-carboxyphenyl)-4-oxybutyric acid synthase;
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AltName:
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Full=o-succinylbenzoic acid synthase;
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Function |
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). |
Catalytic activity |
RHEA:10196: (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate = 2-succinylbenzoate + H2O
EC 4.2.1.113
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Cofactor |
a divalent metal cation |
Pathway |
Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 4/7. |
case not <OC:Cyanobacteria>
Pathway |
Quinol/quinone metabolism; menaquinone biosynthesis. |
else case <OC:Cyanobacteria>
Pathway |
Cofactor biosynthesis; phylloquinone biosynthesis. |
end case
Similarity |
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily. |
case not <OC:Cyanobacteria>
end case
case <FTGroup:1>
end case
GO:0016836; Molecular function: hydro-lyase activity.
case <FTGroup:1>
GO:0000287; Molecular function: magnesium ion binding.
end case
case not <OC:Cyanobacteria>
GO:0009234; Biological process: menaquinone biosynthetic process.
else case <OC:Cyanobacteria>
GO:0042372; Biological process: phylloquinone biosynthetic process.
end case
From: MENC_ECOLI (P29208) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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133
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133
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Proton donor
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K
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ACT_SITE
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235
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235
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Proton acceptor
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K
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METAL
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161
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161
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Magnesium
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D
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1
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METAL
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190
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190
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Magnesium
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E
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1
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METAL
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213
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213
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Magnesium
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D
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1
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Additional information
[?]
Size range |
304-400 amino acids |
Related rules |
None |
Fusion |
None |