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HAMAP rule MF_00490

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General rule information [?]

Accession MF_00490
Dates 26-NOV-2001 (Created)
1-JUN-2023 (Last updated, Version 31)
Name ComB
Scope(s) Bacteria
Template(s) Q58540 (COMB_METJA); [ Recover all ]
Triggered by HAMAP; MF_00490 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier COMB
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Protein name RecName: Full=2-phosphosulfolactate phosphatase;
Protein name RecName: Full=Probable 2-phosphosulfolactate phosphatase;
end case
Gene name Name=comB;

Comments [?]

CATALYTIC ACTIVITY Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377, ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
PATHWAYCofactor biosynthesis; coenzyme M biosynthesis; sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 2/4.
end case
SIMILARITYBelongs to the ComB family.

Keywords [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Coenzyme M biosynthesis
end case

Gene Ontology [?]

GO:0000287; Molecular function:magnesium ion binding
GO:0050532; Molecular function:2-phosphosulfolactate phosphatase activity
case <OCellular component:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
GO:0019295; Biological process:coenzyme M biosynthetic process
end case

Cross-references [?]

Pfam PF04029; 2-ph_phosp; 1;
NCBIfam TIGR00298; TIGR00298; 1;

Features [?]

Additional information [?]

Size range 212-247 amino acids
Related rules None
Fusion Nter: None Cter: None

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