HAMAP rule MF_00490

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00490
Accession	MF_00490
Dates	28-FEB-2005 (Created) 01-JUN-2023 (Last updated, Version 22)
Name	ComB
Scope(s)	Bacteria Archaea
Template(s)	Q58540; [ Recover all ]
Triggered by	HAMAP; MF_00490 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	COMB
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Protein name	RecName: Full=2-phosphosulfolactate phosphatase; EC=3.1.3.71;
else
Protein name	RecName: Full=Probable 2-phosphosulfolactate phosphatase; EC=3.1.3.71;
end case
Gene name	Name=comB;

Comments [?]

CATALYTIC ACTIVITY	Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377, ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
COFACTOR	Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
PATHWAY	Cofactor biosynthesis; coenzyme M biosynthesis; sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 2/4.
end case
SIMILARITY	Belongs to the ComB family.

Keywords [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Coenzyme M biosynthesis
end case
Hydrolase
Magnesium

Gene Ontology [?]

GO:0000287; Molecular function:magnesium ion binding
GO:0050532; Molecular function:2-phosphosulfolactate phosphatase activity
case <OCellular component:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
GO:0019295; Biological process:coenzyme M biosynthetic process
end case

Cross-references [?]

Pfam	PF04029; 2-ph_phosp; 1;
NCBIfam	TIGR00298; TIGR00298; 1;

Features [?]

Additional information [?]

Size range	212-247 amino acids
Related rules	None
Fusion	Nter: None Cter: None

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