HAMAP rule MF_00490
General rule information
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| Accession | MF_00490 |
| Dates | 26-NOV-2001 (Created)
1-JUN-2023 (Last updated, Version 31) |
| Name | ComB |
| Scope(s) |
Bacteria Archaea |
| Template(s) | Q58540 (COMB_METJA); [ Recover all ] |
| Triggered by |
HAMAP; MF_00490 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | COMB |
| case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| Protein name | RecName: Full=2-phosphosulfolactate phosphatase; EC=3.1.3.71; |
| else | |
| Protein name | RecName: Full=Probable 2-phosphosulfolactate phosphatase; EC=3.1.3.71; |
| end case | |
| Gene name | Name=comB; |
Comments
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| CATALYTIC ACTIVITY | Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377, ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71; |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
| case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| PATHWAY | Cofactor biosynthesis; coenzyme M biosynthesis; sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 2/4. |
| end case | |
| SIMILARITY | Belongs to the ComB family. |
Keywords
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| case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| Coenzyme M biosynthesis | |
| end case | |
| Hydrolase | |
| Magnesium | |
Gene Ontology
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| GO:0000287; Molecular function:magnesium ion binding | |
| GO:0050532; Molecular function:2-phosphosulfolactate phosphatase activity | |
| case <OCellular component:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
| GO:0019295; Biological process:coenzyme M biosynthetic process | |
| end case | |
Cross-references
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Features
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Additional information
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| Size range | 212-247 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |