HAMAP rule MF_00491
General rule information
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Accession | MF_00491 |
Dates | 31-OCT-2001 (Created) 17-FEB-2023 (Last updated, Version 40) |
Name | NDH1_NuoM |
Scope | Bacteria; Cyanobacteriota
Plastid |
Template | P72823 (NU4C2_SYNY3) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
|
case not <OG:Chloroplast>
Protein name |
|
end case
case <OG:Chloroplast>
Protein name |
|
end case
Gene name |
|
Comments
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case not <OG:Chloroplast>
Function | NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. |
end case
Catalytic activity | RHEA:42608: a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+) |
RHEA:42612: a plastoquinone + (n+1) H(+)(in) + NADPH = a plastoquinol + n H(+)(out) + NADP(+) |
case <OG:Chloroplast>
Subcellular location | Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. |
else case <OC:Gloeobacter>
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
else
Subcellular location | Cellular thylakoid membrane; Multi-pass membrane protein. |
end case
Similarity | Belongs to the complex I subunit 4 family. |
Keywords
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case <OC:Gloeobacter>
else
end case
Gene Ontology
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GO:0016655; Molecular function: oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
case <OG:Chloroplast>
GO:0009535; Cellular component: chloroplast thylakoid membrane.
else case <OC:Gloeobacter>
GO:0005886; Cellular component: plasma membrane.
else
GO:0042651; Cellular component: thylakoid membrane.
end case
Cross-references
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Computed features
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General | Transmembrane; -; 12-15; trigger=yes; |
Additional information
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Size range | 493-563 amino acids |
Related rules | None |
Fusion | None |
Comments | In dicots the initiation codon seems to be created by RNA editing (has been proven for TOBAC, ARATH, SPIOL, OENEH and snapdragon). |