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HAMAP rule MF_00501

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General rule information [?]

Accession MF_00501
Dates 8-DEC-2001 (Created)
1-JUN-2023 (Last updated, Version 39)
Name Ribosomal_L31_1
Scope
Bacteria
Plastid
Templates Q03223 (RL31_BACSU); Q9RW44 (RL31_DEIRA): [Recover all]
case <OC:Bacteria> or <OG:Chloroplast>
Triggered by
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

case <OC:Bacteria> and not <OC:Cyanobacteriota>
Identifier
RL31
Protein name
RecName: Full=Large ribosomal subunit protein bL31;
Gene name
rpmE
else case <OC:Cyanobacteriota>
Identifier
RL31
Protein name
RecName: Full=Large ribosomal subunit protein bL31;
Gene name
rpmE, rpl31
else case <OG:Chloroplast>
Identifier
RK31
Protein name
RecName: Full=Large ribosomal subunit protein bL31c;
Gene name
rpl31
end case

Comments [?]

Function Binds the 23S rRNA.
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit.
end case
Subunit Part of the 50S ribosomal subunit.
case <OG:Chloroplast>
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.

Keywords [?]

case <FT:5>
Acetylation
end case
Ribonucleoprotein
Ribosomal protein
RNA-binding
rRNA-binding
case <FTGroup:1>
Zinc
Metal-binding
end case

Gene Ontology [?]

GO:0006412; Biological process: translation.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF01197; Ribosomal_L31; 1;
PRINTS PR01249; RIBOSOMALL31; 1;
NCBIfam TIGR00105; L31; 1;
PROSITE PS01143; RIBOSOMAL_L31; 1;

Features [?]

From: RL31_BACSU (Q03223)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     16     16       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING (Optional)     18     18       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING (Optional)     36     36       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
BINDING (Optional)     39     39       /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105     C   1
case <OC:Escherichia> or <OC:Shigella>
From: RL31_ECOLI (P0A7M9)
MOD_RES     8     8       N6-acetyllysine     K  
end case

Additional information [?]

Size range 65-97 amino acids
Related rules MF_00502 (RL31B supersedes the current rule)
Fusion Nter: None; Cter: <Unknown>
Comments Fused with an unknown domain in ANADE. In some bacteria, for example E.coli and B.subtilis, there are paralogous RL31 proteins. In most bacteria with both proteins the protein that corresponds to this family (RL31, rpmE) is thought to be able to bind zinc, while the other member (RL31B, MF_00502, rpmE2) is not able to bind zinc. It has been suggested based on this observation and experiments in B. subtilis that the non-zinc-binding protein will only be made under conditions of zinc-starvation, allowing the cell to economize on the trace metal, see: PubMed=11574053; Makarova K.S., Ponomarev V.A., Koonin E.V.; "Two C or not two C: recurrent disruption of Zn-ribbons, gene duplication, lineage-specific gene loss, and horizontal gene transfer in evolution of bacterial ribosomal proteins."; Genome Biol. 2:RESEARCH 0033-RESEARCH 0033(2001). and PubMed=12904577; DOI=10.1073/pnas.1733691100; Panina E.M., Mironov A.A., Gelfand M.S.; "Comparative genomics of bacterial zinc regulons: enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins."; Proc. Natl. Acad. Sci. U.S.A. 100:9912-9917(2003).


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