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Annotation rule MF_00502
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General rule information [?]

Accession MF_00502
Dates 8-DEC-2001 (Created)
18-NOV-2019 (Last updated, Version 26)
Name Ribosomal_L31_2
Scope
Bacteria
Template O34967 (RL31B_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RL31B
Protein name
RecName: Full=50S ribosomal protein L31 type B;
Gene name
rpmE2

Comments [?]

Subunit Part of the 50S ribosomal subunit.
Similarity Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.

Keywords [?]


Gene Ontology [?]

GO:0006412; Biological process: translation.

Cross-references [?]

Pfam PF01197; Ribosomal_L31; 1;
PRINTS PR01249; RIBOSOMALL31; 1;
TIGRFAMs TIGR00105; L31; 1;
PROSITE PS01143; RIBOSOMAL_L31; 1;

Additional information [?]

Size range 80-117 amino acids
Related rules MF_00501 (RL31)
Fusion None
Comments In some bacteria, for example E.coli and B.subtilis, there are paralogous RL31 proteins. In most bacteria with both proteins the protein that corresponds to the other family (RL31, MF_00501, rpmE) is thought to be able to bind zinc, while this member (RL31B, rpmE2) is not able to bind zinc. It has been suggested based on this observation and experiments in B. subtilis that the non-zinc-binding protein will only be made under conditions of zinc-starvation, allowing the cell to economize on the trace metal, see: PubMed=11574053; Makarova K.S., Ponomarev V.A., Koonin E.V.; "Two C or not two C: recurrent disruption of Zn-ribbons, gene duplication, lineage-specific gene loss, and horizontal gene transfer in evolution of bacterial ribosomal proteins."; Genome Biol. 2:RESEARCH 0033-RESEARCH 0033(2001). and PubMed=12904577; DOI=10.1073/pnas.1733691100; Panina E.M., Mironov A.A., Gelfand M.S.; "Comparative genomics of bacterial zinc regulons: enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins."; Proc. Natl. Acad. Sci. U.S.A. 100:9912-9917(2003).