HAMAP rule MF_00509
General rule information
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| Accession | MF_00509 |
| Dates | 16-DEC-2001 (Created)
1-JUN-2023 (Last updated, Version 36) |
| Name | ZipA |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P77173 (ZIPA_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00509 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ZIPA |
| Protein name | RecName: Full=Cell division protein ZipA; |
| Gene name | Name=zipA; |
Comments
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| FUNCTION | Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. |
| SUBUNIT | Interacts with FtsZ via their C-terminal domains. |
| SUBCELLULAR LOCATION | Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner. |
| SIMILARITY | Belongs to the ZipA family. |
Keywords
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| Cell cycle |
| Cell division |
| Cell inner membrane |
| Cell membrane |
| Membrane |
| Transmembrane |
| Transmembrane helix |
Gene Ontology
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| GO:0043093; Biological process:FtsZ-dependent cytokinesis |
| GO:0032153; Cellular component:cell division site |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF04354; ZipA_C; 1; |
| NCBIfam | TIGR02205; septum_zipA; 1; |
| General | Transmembrane; -; 1; |
| ADD_TOPO_DOMAIN | Periplasmic; -; 1; |
| ADD_TOPO_DOMAIN | Cytoplasmic; -; 1; |
Features
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Additional information
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| Size range | 230-400 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |