HAMAP rule MF_00515
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00515 |
| Accession | MF_00515 |
| Dates | 28-FEB-2005 (Created)
03-SEP-2024 (Last updated, Version 18) |
| Name | MTOX |
| Scope(s) |
Bacteria Enterobacterales |
| Template(s) | P40874; [ Recover all ] |
| Triggered by |
HAMAP; MF_00515 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | MTOX |
| Protein name | RecName: Full=N-methyl-L-tryptophan oxidase; Short=MTOX; EC=1.5.3.-; |
| Gene name | Name=solA; |
Comments
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| FUNCTION | Catalyzes the oxidative demethylation of N-methyl-L- tryptophan. |
| CATALYTIC ACTIVITY | Reaction=N(alpha)-methyl-L-tryptophan + O2 + H2O = L-tryptophan + formaldehyde + H2O2; Xref=Rhea:RHEA:28006, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:16842, ChEBI:CHEBI:57283, ChEBI:CHEBI:57912; |
| COFACTOR | Name=FAD; Xref=ChEBI:CHEBI:57692; Note=Binds 1 FAD per subunit.; |
| SUBUNIT | Monomer. |
| SIMILARITY | Belongs to the MSOX/MTOX family. MTOX subfamily. |
Keywords
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Gene Ontology
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| GO:0016647; Molecular function:oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor |
Cross-references
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| Pfam | PF01266; DAO; 1; |
Features
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| From: MTOX_ECOLI (P40874) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 4 | 34 | /ligand="FAD" /ligand_id="ChEBI:CHEBI:57692" |
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| MOD_RES | 308 | 308 | /note="S-8alpha-FAD cysteine" | C | ||||||||
Additional information
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| Size range | 371-372 amino acids |
| Related rules |
MF_00516 |
| Fusion | Nter: None Cter: None |