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HAMAP rule MF_00519

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General rule information [?]

Accession MF_00519
Dates 18-DEC-2001 (Created)
19-NOV-2022 (Last updated, Version 31)
Name Arabinose_Isome
Scope(s) Bacteria
Template(s) P08202 (ARAA_ECOLI); Q9S467 (ARAA_GEOSE); [ Recover all ]
Triggered by HAMAP; MF_00519 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ARAA
Protein name RecName: Full=L-arabinose isomerase;
Gene name Name=araA;

Comments [?]

FUNCTIONCatalyzes the conversion of L-arabinose to L-ribulose.
CATALYTIC ACTIVITY Reaction=beta-L-arabinopyranose = L-ribulose; Xref=Rhea:RHEA:14821, ChEBI:CHEBI:16880, ChEBI:CHEBI:40886; EC=;
case <FTGroup:1>
COFACTOR Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Note=Binds 1 Mn(2+) ion per subunit.;
end case
PATHWAYCarbohydrate degradation; L-arabinose degradation via L- ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3.
case <OC:Enterobacterales>
end case
SIMILARITYBelongs to the arabinose isomerase family.

Keywords [?]

Gene Ontology [?]

GO:0008733; Molecular function:L-arabinose isomerase activity
case <FTGroup:1>
GO:0030145; Molecular function:manganese ion binding
end case
GO:0019569; Biological process:L-arabinose catabolic process to xylulose 5-phosphate

Cross-references [?]

Pfam PF02610; Arabinose_Isome; 1;

Features [?]

From: ARAA_ECOLI (P08202)
Key From To Description Tag Condition FTGroup
BINDING 306 306 /ligand="Mn(2+)"
E 1
BINDING 333 333 /ligand="Mn(2+)"
E 1
BINDING 350 350 /ligand="Mn(2+)"
H 1
BINDING 450 450 /ligand="Mn(2+)"
H 1

Additional information [?]

Size range 474-511 amino acids
Related rules None
Fusion Nter: None Cter: None

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