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HAMAP rule MF_00519

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General rule information [?]

Accession MF_00519
Dates 18-DEC-2001 (Created)
19-NOV-2022 (Last updated, Version 31)
Name Arabinose_Isome
Templates P08202 (ARAA_ECOLI); Q9S467 (ARAA_GEOSE): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=L-arabinose isomerase;
Gene name

Comments [?]

Function Catalyzes the conversion of L-arabinose to L-ribulose.
Catalytic activity RHEA:14821: beta-L-arabinopyranose = L-ribulose
case <FTGroup:1>
Cofactor Mn(2+)
Note: Binds 1 Mn(2+) ion per subunit.
end case
Pathway Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3.
case <OC:Enterobacterales>
Subunit Homohexamer.
end case
Similarity Belongs to the arabinose isomerase family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0008733; Molecular function: L-arabinose isomerase activity.
case <FTGroup:1>
GO:0030145; Molecular function: manganese ion binding.
end case
GO:0019569; Biological process: L-arabinose catabolic process to xylulose 5-phosphate.

Cross-references [?]

Pfam PF02610; Arabinose_Isome; 1;

Features [?]

From: ARAA_ECOLI (P08202)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     306     306       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035     E   1
BINDING     333     333       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035     E   1
BINDING     350     350       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035     H   1
BINDING     450     450       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035     H   1

Additional information [?]

Size range 474-511 amino acids
Related rules None
Fusion None