HAMAP rule MF_00519
General rule information
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| Accession | MF_00519 |
| Dates | 18-DEC-2001 (Created) 19-NOV-2022 (Last updated, Version 31) |
| Name | Arabinose_Isome |
| Scope | Bacteria |
| Templates | P08202 (ARAA_ECOLI); Q9S467 (ARAA_GEOSE): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the conversion of L-arabinose to L-ribulose. |
| Catalytic activity | RHEA:14821: beta-L-arabinopyranose = L-ribulose
EC 5.3.1.4 |
case <FTGroup:1>
| Cofactor | Mn(2+) Note: Binds 1 Mn(2+) ion per subunit. |
end case
| Pathway | Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. |
case <OC:Enterobacterales>
| Subunit | Homohexamer. |
end case
| Similarity | Belongs to the arabinose isomerase family. |
Keywords
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case <FTGroup:1>
end case
Gene Ontology
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GO:0008733; Molecular function: L-arabinose isomerase activity.
case <FTGroup:1>
GO:0030145; Molecular function: manganese ion binding.
end case
GO:0019569; Biological process: L-arabinose catabolic process to xylulose 5-phosphate.
Cross-references
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| Pfam | PF02610; Arabinose_Isome; 1; |
Features
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| From: ARAA_ECOLI (P08202) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 306 | 306 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035 | E | 1 | |||||||
| BINDING | 333 | 333 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035 | E | 1 | |||||||
| BINDING | 350 | 350 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035 | H | 1 | |||||||
| BINDING | 450 | 450 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035 | H | 1 | |||||||
Additional information
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| Size range | 474-511 amino acids |
| Related rules | None |
| Fusion | None |