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HAMAP rule MF_00519

General rule information [?]

Accession	MF_00519
Dates	18-DEC-2001 (Created) 19-NOV-2022 (Last updated, Version 31)
Name	Arabinose_Isome
Scope(s)	Bacteria
Template(s)	P08202 (ARAA_ECOLI); Q9S467 (ARAA_GEOSE); [ Recover all ]
Triggered by	HAMAP; MF_00519 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	ARAA
Protein name	RecName: Full=L-arabinose isomerase; EC=5.3.1.4;
Gene name	Name=araA;

Comments [?]

FUNCTION	Catalyzes the conversion of L-arabinose to L-ribulose.
CATALYTIC ACTIVITY	Reaction=beta-L-arabinopyranose = L-ribulose; Xref=Rhea:RHEA:14821, ChEBI:CHEBI:16880, ChEBI:CHEBI:40886; EC=5.3.1.4;
case <FTGroup:1>
COFACTOR	Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Note=Binds 1 Mn(2+) ion per subunit.;
end case
PATHWAY	Carbohydrate degradation; L-arabinose degradation via L- ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3.
case <OC:Enterobacterales>
SUBUNIT	Homohexamer.
end case
SIMILARITY	Belongs to the arabinose isomerase family.

Keywords [?]

Gene Ontology [?]

GO:0008733; Molecular function:L-arabinose isomerase activity
case <FTGroup:1>
GO:0030145; Molecular function:manganese ion binding
end case
GO:0019569; Biological process:L-arabinose catabolic process to xylulose 5-phosphate

Cross-references [?]

Pfam	PF02610; Arabinose_Isome; 1;

Features [?]

From: ARAA_ECOLI (P08202)

Key

From

Description

Tag

Condition

FTGroup

BINDING

306

/ligand="Mn(2+)"
/ligand_id="ChEBI:CHEBI:29035"

BINDING

333

/ligand="Mn(2+)"
/ligand_id="ChEBI:CHEBI:29035"

BINDING

350

/ligand="Mn(2+)"
/ligand_id="ChEBI:CHEBI:29035"

BINDING

450

/ligand="Mn(2+)"
/ligand_id="ChEBI:CHEBI:29035"

Additional information [?]