HAMAP rule MF_00524
General rule information
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| Accession | MF_00524 |
| Dates | 16-JAN-2002 (Created)
3-SEP-2024 (Last updated, Version 31) |
| Name | Glucokinase |
| Scope(s) |
Bacteria |
| Template(s) | P0A6V8 (GLK_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00524 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | GLK |
| Protein name | RecName: Full=Glucokinase; EC=2.7.1.2; AltName: Full=Glucose kinase; |
| Gene name | Name=glk; |
Comments
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| CATALYTIC ACTIVITY | Reaction=D-glucose + ATP = D-glucose 6-phosphate + ADP + H(+); Xref=Rhea:RHEA:17825, ChEBI:CHEBI:4167, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:61548, ChEBI:CHEBI:456216; EC=2.7.1.2; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the bacterial glucokinase family. |
Keywords
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Gene Ontology
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| GO:0005524; Molecular function:ATP binding |
| GO:0004340; Molecular function:glucokinase activity |
| GO:0006096; Biological process:glycolytic process |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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| From: GLK_ECOLI (P0A6V8) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 8 | 13 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
x-D-[IV]-G-G-[ST] | ||||||||
Additional information
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| Size range | 319-355 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: <Unknown> |
| Comments | The Burkholderia are fused with a possible like a transcriptional regulator. Divergent glk-like proteins in CAUVC and XYLFA |