HAMAP rule MF_00538

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_00538
Accession	MF_00538
Dates	28-FEB-2005 (Created) 01-MAR-2024 (Last updated, Version 36)
Name	Flippase_ArnF
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P76474; [ Recover all ]
Triggered by	HAMAP; MF_00538 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	ARNF
Protein name	RecName: Full=Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Short=L-Ara4N-phosphoundecaprenol flippase subunit ArnF; AltName: Full=Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF;
Gene name	Name=arnF;

Comments [?]

FUNCTION	Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
PATHWAY	Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
SUBUNIT	Heterodimer of ArnE and ArnF.
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
SIMILARITY	Belongs to the ArnF family.

Keywords [?]

Cell inner membrane

Lipid A biosynthesis

Lipid biosynthesis

Lipid metabolism

Lipopolysaccharide biosynthesis

Transmembrane helix

Gene Ontology [?]

GO:0009245; Biological process:lipid A biosynthetic process

GO:0009103; Biological process:lipopolysaccharide biosynthetic process

GO:0055085; Biological process:transmembrane transport

GO:0022857; Molecular function:transmembrane transporter activity

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam	PF00892; EamA; 0-1;
General	Transmembrane; -; 4;
ADD_TOPO_DOMAIN	Cytoplasmic; -; 3;
ADD_TOPO_DOMAIN	Periplasmic; -; 2;

Features [?]

Additional information [?]

Size range	125-148 amino acids
Related rules	None
Fusion	Nter: None Cter: None

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