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Annotation rule MF_00538
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General rule information [?]

Accession MF_00538
Dates 19-FEB-2002 (Created)
18-NOV-2019 (Last updated, Version 42)
Name Flippase_ArnF
Scope
Bacteria; Gammaproteobacteria
Template P76474 (ARNF_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ARNF
Protein name
RecName: Full=Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF;
Short=L-Ara4N-phosphoundecaprenol flippase subunit ArnF;
AltName: Full=Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF;
Gene name
arnF

Comments [?]

Function Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
Pathway Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
Subunit Heterodimer of ArnE and ArnF.
Subcellular location Cell inner membrane; Multi-pass membrane protein.
Similarity Belongs to the ArnF family.

Keywords [?]

Cell inner membrane
Cell membrane
Lipid A biosynthesis
Lipid biosynthesis
Lipid metabolism
Lipopolysaccharide biosynthesis
Membrane
Transmembrane
Transport
Transmembrane helix

Gene Ontology [?]

GO:0009245; Biological process: lipid A biosynthetic process.
GO:0055085; Biological process: transmembrane transport.
GO:0022857; Molecular function: transmembrane transporter activity.
GO:0005887; Cellular component: integral component of plasma membrane.

Cross-references [?]

Pfam PF00892; EamA; 0-1; trigger=Yes;

Computed features [?]

General Transmembrane; -; 4; trigger=yes;
ADD_TOPO_DOMAIN Cytoplasmic; -; 3; trigger=yes;
Periplasmic; -; 2; trigger=yes;

Additional information [?]

Size range 125-148 amino acids
Related rules None
Fusion None


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