HAMAP rule MF_00538
General rule information
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| Accession | MF_00538 |
| Dates | 19-FEB-2002 (Created)
29-SEP-2022 (Last updated, Version 43) |
| Name | Flippase_ArnF |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P76474 (ARNF_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00538 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ARNF |
| Protein name | RecName: Full=Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Short=L-Ara4N-phosphoundecaprenol flippase subunit ArnF; AltName: Full=Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF; |
| Gene name | Name=arnF; |
Comments
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| FUNCTION | Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane. |
| PATHWAY | Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. |
| SUBUNIT | Heterodimer of ArnE and ArnF. |
| SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
| SIMILARITY | Belongs to the ArnF family. |
Keywords
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| Cell inner membrane |
| Cell membrane |
| Lipid A biosynthesis |
| Lipid biosynthesis |
| Lipid metabolism |
| Lipopolysaccharide biosynthesis |
| Membrane |
| Transmembrane |
| Transport |
| Transmembrane helix |
Gene Ontology
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| GO:0009245; Biological process:lipid A biosynthetic process |
| GO:0055085; Biological process:transmembrane transport |
| GO:0022857; Molecular function:transmembrane transporter activity |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF00892; EamA; 0-1; |
| General | Transmembrane; -; 4; |
| ADD_TOPO_DOMAIN | Cytoplasmic; -; 3; |
| ADD_TOPO_DOMAIN | Periplasmic; -; 2; |
Features
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Additional information
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| Size range | 125-148 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |