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HAMAP rule MF_00541

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General rule information [?]

Accession MF_00541
Dates 1-MAR-2002 (Created)
12-MAR-2024 (Last updated, Version 38)
Name RhaA
Scope(s) Bacteria
Template(s) P32170 (RHAA_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_00541 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RHAA
Protein name RecName: Full=L-rhamnose isomerase;
                 EC=5.3.1.14;
Gene name Name=rhaA;

Comments [?]

FUNCTIONCatalyzes the interconversion of L-rhamnose and L-rhamnulose.
CATALYTIC ACTIVITY Reaction=L-rhamnopyranose = L-rhamnulose; Xref=Rhea:RHEA:23160, ChEBI:CHEBI:17897, ChEBI:CHEBI:62346; EC=5.3.1.14;
case <FTGroup:1>
COFACTOR Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Note=Binds 1 Mn(2+) ion per subunit.;
end case
PATHWAYCarbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 1/3.
case <OC:Enterobacterales>
SUBUNITHomotetramer.
end case
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the rhamnose isomerase family.

Keywords [?]


Gene Ontology [?]

GO:0008740; Molecular function:L-rhamnose isomerase activity
case <FTGroup:1>
GO:0030145; Molecular function:manganese ion binding
end case
GO:0019301; Biological process:rhamnose catabolic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF06134; RhaA; 1;
NCBIfam TIGR01748; RhaA; 1;

Features [?]

From: RHAA_ECOLI (P32170)
Key From To Description Tag Condition FTGroup
BINDING 262 262 /ligand="Mn(2+)"
/ligand_id="ChEBI:CHEBI:29035"
H 1
BINDING 294 294 /ligand="Mn(2+)"
/ligand_id="ChEBI:CHEBI:29035"
D 1
BINDING 296 296 /ligand="Mn(2+)"
/ligand_id="ChEBI:CHEBI:29035"
D 1

Additional information [?]

Size range 417-428 amino acids
Related rules None
Fusion Nter: MF_01535 (rhaB) Cter: None



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