HAMAP rule MF_00541
General rule information
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| Accession | MF_00541 |
| Dates | 1-MAR-2002 (Created)
12-MAR-2024 (Last updated, Version 38) |
| Name | RhaA |
| Scope(s) |
Bacteria |
| Template(s) | P32170 (RHAA_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00541 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RHAA |
| Protein name | RecName: Full=L-rhamnose isomerase; EC=5.3.1.14; |
| Gene name | Name=rhaA; |
Comments
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| FUNCTION | Catalyzes the interconversion of L-rhamnose and L-rhamnulose. |
| CATALYTIC ACTIVITY | Reaction=L-rhamnopyranose = L-rhamnulose; Xref=Rhea:RHEA:23160, ChEBI:CHEBI:17897, ChEBI:CHEBI:62346; EC=5.3.1.14; |
| case <FTGroup:1> | |
| COFACTOR | Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Note=Binds 1 Mn(2+) ion per subunit.; |
| end case | |
| PATHWAY | Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 1/3. |
| case <OC:Enterobacterales> | |
| SUBUNIT | Homotetramer. |
| end case | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the rhamnose isomerase family. |
Keywords
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| Cytoplasm | |
| Isomerase | |
| case <FTGroup:1> | |
| Manganese | |
| Metal-binding | |
| end case | |
| Rhamnose metabolism | |
Gene Ontology
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| GO:0008740; Molecular function:L-rhamnose isomerase activity | |
| case <FTGroup:1> | |
| GO:0030145; Molecular function:manganese ion binding | |
| end case | |
| GO:0019301; Biological process:rhamnose catabolic process | |
| GO:0005737; Cellular component:cytoplasm | |
Cross-references
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Features
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| From: RHAA_ECOLI (P32170) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 262 | 262 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" |
H | 1 | |||||||
| BINDING | 294 | 294 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" |
D | 1 | |||||||
| BINDING | 296 | 296 | /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035" |
D | 1 | |||||||
Additional information
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| Size range | 417-428 amino acids |
| Related rules |
None |
| Fusion | Nter: MF_01535 (rhaB) Cter: None |