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HAMAP rule MF_00565

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General rule information [?]

Accession MF_00565
Dates 29-JUN-2002 (Created)
1-JUN-2023 (Last updated, Version 32)
Name DltC
Scope(s) Bacteria
Template(s) P39579 (DLTC_BACSU); P55153 (DLTC_LACRH); Q2FZW4 (DLTC_STAA8); [ Recover all ]
Triggered by HAMAP; MF_00565 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DLTC
Protein name RecName: Full=D-alanyl carrier protein;
AltName: Full=D-alanine--poly(phosphoribitol) ligase subunit 2;
Gene name Name=dltC;

Comments [?]

FUNCTIONCarrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
PATHWAYCell wall biogenesis; lipoteichoic acid biosynthesis.
PTM4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
SIMILARITYBelongs to the DltC family.

Keywords [?]

Gene Ontology [?]

GO:0036370; Molecular function:D-alanyl carrier activity
GO:0005737; Cellular component:cytoplasm
GO:0070395; Biological process:lipoteichoic acid biosynthetic process

Cross-references [?]

Pfam PF00550; PP-binding; 1;
NCBIfam TIGR01688; DltC; 1;

Features [?]

From: DLTC_BACSU (P39579)
Key From To Description Tag Condition FTGroup
MOD_RES 36 36 /note="O-(pantetheine 4'-phosphoryl)serine" S

Additional information [?]

Size range 75-83 amino acids
Related rules None
Fusion Nter: None Cter: None

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