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Annotation rule MF_00565
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General rule information [?]

Accession MF_00565
Dates 29-JUN-2002 (Created)
18-NOV-2019 (Last updated, Version 31)
Name DltC
Templates P39579 (DLTC_BACSU); P55153 (DLTC_LACRH); Q2FZW4 (DLTC_STAA8): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=D-alanyl carrier protein;
AltName: Full=D-alanine--poly(phosphoribitol) ligase subunit 2;
Gene name

Comments [?]

Function Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
Pathway Cell wall biogenesis; lipoteichoic acid biosynthesis.
Subcellular location Cytoplasm.
Ptm 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-DCP.
Similarity Belongs to the DltC family.

Keywords [?]

Gene Ontology [?]

GO:0036370; Molecular function: D-alanyl carrier activity.
GO:0005737; Cellular component: cytoplasm.
GO:0070395; Biological process: lipoteichoic acid biosynthetic process.

Cross-references [?]

Pfam PF00550; PP-binding; 1;
TIGRFAMs TIGR01688; DltC; 1;
PROSITE PS50075; CARRIER; 1; trigger=PRU00258;

Features [?]

From: DLTC_BACSU (P39579)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     36     36       O-(pantetheine 4'-phosphoryl)serine     S  

Additional information [?]

Size range 75-83 amino acids
Related rules None
Fusion None