HAMAP logo

HAMAP rule MF_00590

Send feedback

General rule information [?]

PURL https://purl.expasy.org/hamap/rule/MF_00590
Accession MF_00590
Dates 28-OCT-2002 (Created)
3-SEP-2024 (Last updated, Version 25)
Name Dephospho_CoA_kinase_GTP_dep
Scope(s) Archaea
Template(s) Q5JIY7 (DPCKG_THEKO); [ Recover all ]
Triggered by HAMAP; MF_00590 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier DPCKG
Protein name RecName: Full=GTP-dependent dephospho-CoA kinase;
                 EC=2.7.1.237;
AltName: Full=Dephospho-coenzyme A kinase;
                 Short=DPCK;

Comments [?]

FUNCTIONCatalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
CATALYTIC ACTIVITY Reaction=3'-dephospho-CoA + GTP = GDP + CoA + H(+); Xref=Rhea:RHEA:61156, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:57287, ChEBI:CHEBI:57328, ChEBI:CHEBI:58189; EC=2.7.1.237;
PATHWAYCofactor biosynthesis; coenzyme A biosynthesis.
SIMILARITYBelongs to the GTP-dependent DPCK family.

Keywords [?]


Gene Ontology [?]

GO:0016301; Molecular function:kinase activity
GO:0005525; Molecular function:GTP binding
GO:0015937; Biological process:coenzyme A biosynthetic process

Cross-references [?]

Pfam PF04019; DUF359; 1;
NCBIfam NF041125; deph_CoA_kin_Thcocales; 1;
PIRSF PIRSF006533; UCP006533; 1;

Features [?]

From: DPCKG_THEKO (Q5JIY7)
Key From To Description Tag Condition FTGroup
BINDING 48 48 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
D
BINDING 49 49 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
[VLI]
BINDING 50 50 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
V
BINDING 67 67 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
D
BINDING 69 69 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
K
BINDING 124 124 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
[ED]
BINDING 147 147 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
[DE]

Additional information [?]

Size range 140-400 amino acids
Related rules None
Fusion Nter: None Cter: None



View rule in raw text format (no links)