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Annotation rule MF_00591
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General rule information [?]

Accession MF_00591
Dates 5-MAR-2003 (Created)
18-NOV-2019 (Last updated, Version 18)
Name Exosome_Rrp41
Templates Q9UXC2 (RRP41_SACS2); O29757 (RRP41_ARCFU); O26779 (RRP41_METTH); Q9V119 (RRP41_PYRAB): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Exosome complex component Rrp41;
EC 3.1.13.-;
Gene name

Comments [?]

Function Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
Subunit Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
Subcellular location Cytoplasm.
Similarity Belongs to the RNase PH family. Rrp41 subfamily.

Keywords [?]

Gene Ontology [?]

GO:0000175; Molecular function: 3'-5'-exoribonuclease activity.
GO:0006401; Biological process: RNA catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01138; RNase_PH; 1;
PF03725; RNase_PH_C; 1;
TIGRFAMs TIGR02065; ECX1; 1;

Additional information [?]

Size range 230-501 amino acids
Related rules None
Fusion Nter: None; Cter: <Unknown>