HAMAP rule MF_00602

General rule information [?]

Accession	MF_00602
Dates	19-NOV-2002 (Created) 19-NOV-2022 (Last updated, Version 27)
Name	Prot_Arg_kinase
Scope(s)	Bacteria
Template(s)	P37570 (MCSB_BACSU); P0DMM5 (MCSB_GEOSE); [ Recover all ]
Triggered by	HAMAP; MF_00602 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MCSB
Protein name	RecName: Full=Protein-arginine kinase; EC=2.7.14.1;
Gene name	Name=mcsB;

Comments [?]

case <OC:Bacillaceae>
FUNCTION	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
else
FUNCTION	Catalyzes the specific phosphorylation of arginine residues in proteins.
end case
CATALYTIC ACTIVITY	Reaction=ATP + L-arginyl-[protein] = ADP + H(+) + N(omega)-phospho-L- arginyl-[protein]; Xref=Rhea:RHEA:43384, Rhea:RHEA-COMP:10532, Rhea:RHEA-COMP:10533, ChEBI:CHEBI:15378, ChEBI:CHEBI:29965, ChEBI:CHEBI:30616, ChEBI:CHEBI:83226, ChEBI:CHEBI:456216; EC=2.7.14.1;
case <FTTag:Motif>
ACTIVITY REGULATION	Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
end case
SIMILARITY	Belongs to the ATP:guanido phosphotransferase family.

Keywords [?]

Gene Ontology [?]

GO:0016775; Molecular function:phosphotransferase activity, nitrogenous group as acceptor

GO:0004672; Molecular function:protein kinase activity

Cross-references [?]

Features [?]

From: MCSB_BACSU (P37570)

Key

From

Description

Tag

Condition

FTGroup

BINDING